3034203-03-4
3034203-03-4
Chemical Structure
RSK4-IN-2
- CAS No.: 3034203-03-4
- Formula:C17H16N8O
- Molecular Weight:348.36
InChIKey: FMPJLGKTHSPYBF-UHFFFAOYSA-N
SMILES: O=C1N(C2=NC(NC3=CC=C4NN=NC4=C3)=NC=C2N=C1)C5CCCC5
Biological Activity: RSK4-IN-2 (compound 16o) is a potent, orally active RSK4 inhibitor with an IC50 of 17 nM. RSK4-IN-2 suppresses esophageal squamous cell carcinoma (ESCC) cell growth and invasion, by inhibiting phosphorylation of RSK4 downstream targets. RSK4-IN-2 inhibits tumor growth and metastasis in ESCC mouse models. RSK4-IN-2 can be used for ESCC research[1].
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RSK4-IN-2 | RSK4-IN-2 (compound 16o) is a potent, orally active RSK4 inhibitor with an IC50 of 17 nM. RSK4-IN-2 suppresses esophageal squamous cell carcinoma (ESCC) cell growth and invasion, by inhibiting phosphorylation of RSK4 downstream targets. RSK4-IN-2 inhibits tumor growth and metastasis in ESCC mouse models. RSK4-IN-2 can be used for ESCC research. | |||||||||||||||||||||
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