RSK4-IN-2
RSK4-IN-2 (compound 16o) is a potent, orally active RSK4 inhibitor with an IC50 of 17 nM. RSK4-IN-2 suppresses esophageal squamous cell carcinoma (ESCC) cell growth and invasion, by inhibiting phosphorylation of RSK4 downstream targets. RSK4-IN-2 inhibits tumor growth and metastasis in ESCC mouse models. RSK4-IN-2 can be used for ESCC research.
For research use only. We do not sell to patients.
- CAS No.: 3034203-03-4
- Formula: C17H16N8O
- Molecular Weight:348.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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RSK4 17 nM (IC50) |
Chemical Information
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CAS No. 3034203-03-4
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Molecular Weight 348.36
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Formula C17H16N8O
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SMILES
O=C1N(C2=NC(NC3=CC=C4NN=NC4=C3)=NC=C2N=C1)C5CCCC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)