13 Results for "

calculation

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "calculation" in MCE Product Catalog:

L-Cysteine S-sulfate sodium hydrate
L-Cysteine S-sulfate sodium hydrate
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Art. -Nr.: HY-45609
CAS. Nr.: 150465-29-5
Category:  

Natural Products Neurological Disease Endogenous metabolite Disease Research Fields

Target:  

Drug Derivative

L-Cysteine S-sulfate sodium hydrate is an S-sulfated derivative of L-cysteine (HY-Y0337). L-Cysteine S-sulfate sodium hydrate is the substrate for cystine lyase, it can be used in mass spectrometry and chromatography analyses .
Boc-L-Alaninol
Boc-L-Alaninol
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Art. -Nr.: HY-W007729
CAS. Nr.: 79069-13-9
Boc-L-Alaninol is a Boc-protected chiral amino alcohol. Boc-L-Alaninol can be used in the synthesis of optically active bipyridine-containing polymers .
4-Bromo-1H-indazole
4-Bromo-1H-indazole
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Art. -Nr.: HY-69085
CAS. Nr.: 186407-74-9
4-Bromo-1H-indazole is a carbonic anhydrase inhibitor, with an IC50 of 0.403 mM and a Ki of 0.383 mM against hCA-I, as well as an IC50 of 0.700 mM and a Ki of 0.935 mM against hCA-II. 4-Bromo-1H-indazole reduces the catalytic activity of human I and II isoforms of carbonic anhydrase .
5-Methyl-2-furanmethanol
5-Methyl-2-furanmethanol
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Art. -Nr.: HY-W087919
CAS. Nr.: 3857-25-8
Category:  

Natural Products other families Other Diseases Dianthus rupicola Biv. Plants Disease Research Fields

Target:  

Biochemical Assay Reagents

5-Methyl-2-furanmethanol is a caramel flavor compound with an odor threshold of 0.10 mg/kg. 5-Methyl-2-furanmethanol carries a characteristic caramel, bread-like aroma. 5-Methyl-2-furanmethanol can be used in research on cosmetics and flavorings .
JC-9
JC-9
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Art. -Nr.: HY-D1752
CAS. Nr.: 522592-13-8
Synonyms: D-22421
JC-9 (D-22421) is a green-fluorescent probe used for ratiometric calculation of mitochondrial membrane potential.
WEE1-IN-14
WEE1-IN-14
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Art. -Nr.: HY-178150
CAS. Nr.: 2803921-87-9
Target:  

Wee1

Forschungsgebiete:  

Cancer

WEE1-IN-14 (Compound 14) is a selective WEE1 inhibitor (IC50: 0.5 nM in L-RB-FEP calculations, 1.0 nM in ADP-Glo kinase assay). Inhibition of Wee1 in cancer cells disrupts the G2-M checkpoint, removes the regulatory controls on the cell cycle, and leads to early onset of mitotic failure followed by apoptosis of tumor cells. Therefore, WEE1-IN-14 is a useful tool for studying cancer biology .
4-Hydroxycanthin-6-one
4-Hydroxycanthin-6-one
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Art. -Nr.: HY-N12964
CAS. Nr.: 106941-27-9
Category:  

Alkaloids Simaroubaceae Ailanthus altissima (Mill.) Swingle Quinoline Alkaloids Plants

Target:  

Others

4-Hydroxycanthin-6-one is a novel quinoline alkaloid isolated from the stem bark of the tree Ailanthus altissima. Five other known compounds were also found in the study. The structures of the new compounds were determined by interpretation of physical and spectroscopic data, and their absolute configurations were determined by electronic circular dichroism spectroscopy and quantum chemical calculations. These compounds showed significant inhibitory activity against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 cells, showing potential anti-inflammatory properties .
Antifungal agent 81
Antifungal agent 81
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Art. -Nr.: HY-157015
Target:  

Fungal

Forschungsgebiete:  

Infection

Antifungal agent 81(G22)exhibitsexcellent in vitro antifungal activities against Valsa mali withIC50values of 0.48 mg/L. Antifungal agent 81also exhibits excellent in vivo protective againstV. maliat 40 mg/L .
hACE2/SP-IN-1
hACE2/SP-IN-1
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Art. -Nr.: HY-161068
Target:  

SARS-CoV Angiotensin-converting Enzyme (ACE)

Forschungsgebiete:  

Infection

hACE2/SP-IN-1 (compound 7a) is a dual inhibitor of hACE2 and coronavirus spike protein. hACE2/SP-IN-1 can bind to the spike protein and block cell entry, preventing SARS-CoV-2 from infecting human cells .
Crepidiaside B
Crepidiaside B
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Art. -Nr.: HY-N9664
CAS. Nr.: 101921-35-1
Category:  

Terpenoids Sesquiterpenes Plants Compositae Sophora tomentosa L.

Target:  

SARS-CoV Virus Protease

Crepidiaside B is a plant-derived active component that can be found in Cichorium intybus. Crepidiaside B acts as a SARS-CoV-2 spike glycoprotein inhibitor and is used in research related to coronavirus disease 2019 (COVID-19) .
1,3,5-Tri(1H-1,2,3-triazol-5-yl)benzene
1,3,5-Tri(1H-1,2,3-triazol-5-yl)benzene
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Art. -Nr.: HY-W543267
CAS. Nr.: 1167993-47-6
Target:  

MOFs Drug Intermediate

Forschungsgebiete:  

Others

1,3,5-Tri (1H-1,2,3-triazol-5-yl) benzene is a tritopic triazole-bridged ligand (H3BTTri) that forms a sodalite-type metal-organic framework with coordinatively unsaturated cobalt (II) centers. This framework exhibits selective O2-binding capacity over N2. 1,3,5-Tri (1H-1,2,3-triazol-5-yl) benzene can be used for the synthesis of metal-organic framework (MOF)-related materials .
3-(2-Hydroxyethyl)quinazoline-2,4(1H,3H)-dione
3-(2-Hydroxyethyl)quinazoline-2,4(1H,3H)-dione
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Art. -Nr.: HY-W077690
CAS. Nr.: 1207-75-6
Target:  

Bacterial

Forschungsgebiete:  

Infection

3-(2-Hydroxyethyl)quinazoline-2,4(1H,3H)-dione is an metal chelating agent and anti-bacterial agent. 3-(2-Hydroxyethyl)quinazoline-2,4(1H,3H)-dione shows inhibitory activity against gram-positive and gram-negative bacterial strains .
Cholera toxin-IN-1
Cholera toxin-IN-1
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Art. -Nr.: HY-181824
Target:  

Bacterial

Forschungsgebiete:  

Infection

Cholera toxin-IN-1 is a potent competitive inhibitor of cholera toxin B subunit (CTB) with an IC50 value of 11.78 μM. Cholera toxin-IN-1 forms stable hydrogen bonds and hydrophobic interactions. Cholera toxin-IN-1 competitively blocks the binding of CTB to GM1 ganglioside. Cholera toxin-IN-1 can be used for the research of cholera .
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