PNRC1 - proline rich nuclear receptor coactivator 1 Gene

Also Known as B4-2; PRR2; PROL2; PNAS-145

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10957

About PNRC1

Cytogenetic location: 6q15 Genomic coordinates (GRCh38): 6:89,080,751-89,085,160 (from NCBI)

This gene has 3 transcripts (splice variants), 176 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 61.8), adrenal (RPKM 44.5) and 25 other tissues.

Summary

Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

PNRC1 Products (1)

mRNA Protein Name
NM_006813.3 NP_006804.1 proline-rich nuclear receptor coactivator 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
17612402 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PNRC1 Protein Structure

PNRC

PNRC: Proline-rich nuclear receptor coactivator motif (276 - 326)

  • 0
  • 100
  • 200
  • 300
  • 327 a.a.
Protein Preferred Names Protein Names

proline-rich nuclear receptor coactivator 1

  • proline rich 2 protein

PNRC1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
PNRC1 Q12796 POLR3F Homo sapiens Q9H1D9
Anti Tag CoIP
17612402
Intra
PNRC1 Q12796 POLR3F Homo sapiens Q9H1D9
Y2H
17612402
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Uremic Neuropathy
Brachydactyly, Type E2

  • Brachydactyly Type E2

  • BDE2

  • Brachydactyly E2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS10802 PNRC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20083 Pnrc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26586 Pnrc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PNRC1 VGNC VGNC:102485
Canis familiaris PNRC1 VGNC VGNC:44761
Bos taurus PNRC1 VGNC VGNC:33098
Macaca mulatta PNRC1 VGNC VGNC:76045
Rattus norvegicus PNRC1 RGD RGD:628753
Mus musculus PNRC1 MGD MGI:1917838
Others PNRC1 NCBI