ST8SIA6 - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 Gene

Also Known as SIA8F; SIAT8F; SIAT8-F; ST8SiaVI; ST8SIA-VI

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 338596

About ST8SIA6

Cytogenetic location: 10p12.33 Genomic coordinates (GRCh38): 10:17,315,421-17,454,595 (from NCBI)

This gene has 3 transcripts (splice variants), 125 orthologues and 5 paralogues. Broad expression in lung (RPKM 3.3), heart (RPKM 1.0) and 14 other tissues.

Summary

This gene encodes a member of the Glycosyltransferase 29 protein family. Members of this protein family synthesize sialylglycoconjugates. Sialylation may contribute to multidrug resistance in Cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

ST8SIA6 Products (2)

mRNA Protein Name
NM_001004470.3 NP_001004470.1 alpha-2,8-sialyltransferase 8F isoform 1 precursor
NM_001345961.2 NP_001332890.1 alpha-2,8-sialyltransferase 8F isoform 2

ST8SIA6 Protein Structure

Glyco_transf_29

Glyco_transf_29: Glycosyltransferase family 29 (sialyltransferase) (135 - 392)

  • 0
  • 100
  • 200
  • 300
  • 398 a.a.
Protein Preferred Names Protein Names

alpha-2,8-sialyltransferase 8F

  • ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 6

Related Diseases

Diseases Alias
Lice Infestation

  • Pediculosis

  • Louse Infestation

  • Mixed Pediculosis

  • Lice Infestations

  • Infestation By Pediculus

  • Mixed Pediculosis Infestation

  • Pediculosis + Lice

  • Pediculosis And Phthirus Infection

  • Pediculosis And Phthirus Infections

  • Pediculosis And Phthirus Infestation

  • Infestation By Anoplura

  • Pediculus Infestation

  • Lice Nos
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70302 ST8 alpha-2,8-Sialyltransferase 6 / Unkown
HY-RS13860 ST8SIA6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ST8SIA6 MGD MGI:2386797
Rattus norvegicus ST8SIA6 RGD RGD:1303161
Bos taurus ST8SIA6 VGNC VGNC:35347
Canis familiaris ST8SIA6 VGNC VGNC:46868