NPY4R - neuropeptide Y receptor Y4 Gene

Also Known as Y4; PP1; PPYR1; NPY4-R

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 5540

About NPY4R

Cytogenetic location: 10q11.22 Genomic coordinates (GRCh38): 10:46,461,099-46,470,668 (from NCBI)

This gene has 2 transcripts (splice variants), 115 orthologues and 33 paralogues. Biased expression in colon (RPKM 2.9), skin (RPKM 1.7) and 7 other tissues.

Summary

Enables pancreatic polypeptide receptor activity and peptide hormone binding activity. Involved in G protein-coupled receptor signaling pathway. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

NPY4R Products (10)

mRNA Protein Name
NM_001278794.2 NP_001265723.1 neuropeptide Y receptor type 4
XM_017016386.3 XP_016871875.1 neuropeptide Y receptor type 4 isoform X1
NM_005972.6 NP_005963.4 neuropeptide Y receptor type 4
XM_011539937.4 XP_011538239.1 neuropeptide Y receptor type 4 isoform X1
XR_001747124.3
XM_011539936.4 XP_011538238.1 neuropeptide Y receptor type 4 isoform X1
XR_007061972.1
XM_017016387.3 XP_016871876.1 neuropeptide Y receptor type 4 isoform X1
NM_001278794.2 NP_001265723.1 neuropeptide Y receptor type 4
NM_005972.6 NP_005963.4 neuropeptide Y receptor type 4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables pancreatic polypeptide receptor activity IDA
IDA: Inferred from direct assay
7493937 GOA
enables peptide hormone binding IPI
IPI: Inferred from physical interaction
7493937 GOA
Biological Process GO Annotation Evidence References Source
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
7592911 GOA
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
7493937 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NPY4R Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (58 - 322)

  • 0
  • 100
  • 200
  • 300
  • 375 a.a.
Protein Preferred Names Protein Names

neuropeptide Y receptor type 4

  • pancreatic polypeptide receptor 1

Related Diseases

Diseases Alias
Postsurgical Hypothyroidism

  • Postoperative Hypothyroidism

  • Post-Surgical Hypothyroidism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09517 NPY4R Human Pre-designed siRNA Set A / Unkown
HY-RS09518 Npy4r Mouse Pre-designed siRNA Set A / Unkown
HY-RS09519 Npy4r Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus NPY4R MGD MGI:105374
Rattus norvegicus NPY4R RGD RGD:61864
Others NPY4R NCBI