Tnfrsf1a - TNF receptor superfamily member 1A Gene

Also Known as Tnfr1; TNFR-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25625

Summary

Enables protease binding activity; tumor necrosis factor binding activity; and tumor necrosis factor-activated receptor activity. Involved in several processes, including cellular response to estradiol stimulus; regulation of apoptotic process; and regulation of cytokine production. Located in several cellular components, including cell surface; membrane raft; and mitochondrion. Part of protein-containing complex. Used to study ischemia (multiple); middle cerebral artery infarction; myocardial infarction; uveitis; and visual epilepsy. Biomarker of several diseases, including root resorption; sciatic neuropathy; transient cerebral ischemia; type 2 diabetes mellitus; and ureteral obstruction. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; acne; allergic bronchopulmonary aspergillosis; autoimmune disease (multiple); and autosomal dominant familial periodic fever. Orthologous to human TNFRSF1A (TNF Receptor Superfamily member 1A). [provided by Alliance of Genome Resources, Apr 2022]

Tnfrsf1a Products (1)

mRNA Protein Name
NM_013091.2 NP_037223.2 tumor necrosis factor receptor superfamily member 1A precursor
Protein Preferred Names Protein Names

tumor necrosis factor receptor superfamily member 1A

  • TNF-R1

  • TNF-RI

  • TNFR-I

  • p55

  • p60

  • tumor necrosis factor receptor 1

  • tumor necrosis factor receptor superfamily, member 1a

  • tumor necrosis factor receptor type I

Recombinant Tnfrsf1a Proteins

Cat. No. Product Name Accession Purity
HY-P74504 TNF RI/TNFRSF1A Protein, Rat (HEK293, His) P22934/NP_037223.1 (L30-A211) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P74505 TNF RI/TNFRSF1A Protein, Rat (HEK293, Fc) P22934/NP_037223.1 (I22-A211) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991401 GSK2862277 Antagonist 97.85% Phase 2

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-138779 ICCB-19 hydrochloride 99.25% Unkown
HY-N4323 14-Deoxyandrographolide Inhibitor 99.94% Unkown
HY-RS14810 TNFRSF1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174516 Human TNFRSF1A mRNA / Unkown
HY-RS17012 Tnfrsf1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23455 Tnfrsf1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991400 GSK1995057 99.09% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfrsf1a NCBI NCBI:7132