SLC39A8 - Slc39a8 solute carrier family 39 member 8 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 295455

Summary

Enables transition metal ion transmembrane transporter activity. Involved in inorganic cation transmembrane transport. Located in plasma membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIn. Orthologous to human SLC39A8 (solute carrier family 39 member 8). [provided by Alliance of Genome Resources, Apr 2022]

SLC39A8 Products (1)

mRNA Protein Name
NM_001011952.1 NP_001011952.1 metal cation symporter ZIP8 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables monoatomic cation:bicarbonate symporter activity IDA
IDA: Inferred from direct assay
22898811 RGD
enables zinc:bicarbonate symporter activity IDA
IDA: Inferred from direct assay
22898811 RGD
Biological Process GO Annotation Evidence References Source
involved in cadmium ion transmembrane transport IDA
IDA: Inferred from direct assay
22898811 RGD
involved in cobalt ion transport IDA
IDA: Inferred from direct assay
22898811 RGD
involved in iron ion import across plasma membrane IDA
IDA: Inferred from direct assay
22898811 RGD
involved in manganese ion transmembrane transport IDA
IDA: Inferred from direct assay
22898811 RGD
involved in zinc ion import across plasma membrane IDA
IDA: Inferred from direct assay
22898811 RGD
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
22898811 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

metal cation symporter ZIP8

  • ZIP-8

  • solute carrier family 39 (metal ion transporter), member 8

  • solute carrier family 39 (zinc transporter), member 8

  • zinc transporter ZIP8

  • zrt- and Irt-like protein 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-179571 ZIP14-IN-1 Inhibitor 99.82% Unkown
HY-RS13239 SLC39A8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16232 Slc39a8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28561 Slc39a8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SLC39A8 NCBI NCBI:64116