Pafah1b2 - platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64189

Summary

Enables 1-alkyl-2-acetylglycerophosphocholine esterase activity; identical protein binding activity; and platelet-activating factor acetyltransferase activity. Involved in brain development. Located in cytosol. Part of 1-alkyl-2-acetylglycerophosphocholine esterase complex. Human ortholog(s) of this gene implicated in lymphoma. Orthologous to human PAFAH1B2 (platelet activating factor acetylhydrolase 1b catalytic subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Pafah1b2 Products (1)

mRNA Protein Name
NM_022387.3 NP_071782.1 platelet-activating factor acetylhydrolase IB subunit alpha2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables 1-alkyl-2-acetylglycerophosphocholine esterase activity IDA
IDA: Inferred from direct assay
9660828 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
9660828 RGD
enables platelet-activating factor acetyltransferase activity IDA
IDA: Inferred from direct assay
9660828 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
10940388 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
9660828 RGD
Cellular Component GO Annotation Evidence References Source
part of 1-alkyl-2-acetylglycerophosphocholine esterase complex IDA
IDA: Inferred from direct assay
9660828 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

platelet-activating factor acetylhydrolase IB subunit alpha2

  • PAF acetylhydrolase 30 kDa subunit

  • PAF-AH 30 kDa subunit

  • PAF-AH alpha 2

  • PAF-AH subunit beta

  • PAFAH subunit beta

  • platelet-activating factor acetylhydrolase IB subunit beta

  • platelet-activating factor acetylhydrolase alpha 2 subunit (PAF-AH alpha 2)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-111053 P11 Inhibitor 99.69% Unkown
HY-RS09968 PAFAH1B2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21274 Pafah1b2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27793 Pafah1b2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pafah1b2 NCBI NCBI:5049