TUBA1C - tubulin alpha 1c Gene
Also Known as TUBA6; bcm948
Species: Homo sapiens
About TUBA1C
This gene has 9 transcripts (splice variants), 174 orthologues and 23 paralogues. Ubiquitous expression in esophagus (RPKM 168.9), bone marrow (RPKM 156.4) and 25 other tissues.
Summary
Predicted to enable GTP binding activity. Predicted to be a structural constituent of Cytoskeleton. Predicted to be involved in microtubule Cytoskeleton organization and mitotic cell cycle. Located in microtubule Cytoskeleton and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
TUBA1C Products (5)
| mRNA | Protein | Name |
|---|---|---|
| NM_001303114.1 | NP_001290043.1 | tubulin alpha-1C chain isoform a |
| NM_001303115.2 | NP_001290044.1 | tubulin alpha-1C chain isoform b |
| NM_001303116.2 | NP_001290045.1 | tubulin alpha-1C chain isoform b |
| NM_001303117.2 | NP_001290046.1 | tubulin alpha-1C chain isoform b |
| NM_032704.5 | NP_116093.1 | tubulin alpha-1C chain isoform c |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
22720776 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
22720776 | GOA |
TUBA1C Protein Structure
Tubulin: Tubulin/FtsZ family, GTPase domain (3 - 225)
Tubulin_C: Tubulin C-terminal domain (263 - 392)
- 0
- 100
- 200
- 300
- 400
- 449 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
tubulin alpha-1C chain |
|
TUBA1C Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
TUBA1C | Q9BQE3 | VIM | Homo sapiens | P08670 | 27107012 | |
|
Intra
|
TUBA1C | Q9BQE3 | VIM | Homo sapiens | P08670 | 27107012 |
TUBA1C Antibodies
| Cat. No. | Product Name | Application | Reactivity |
|---|---|---|---|
| HY-P811337 | TUBA1C Antibody | WB, IHC-P | Human, Mouse, Rat |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | TUBA1C | MGD | MGI:1095409 |
| Rattus norvegicus | TUBA1C | RGD | RGD:1307226 |
| Others | TUBA1C | NCBI |