PLAP-IN-1
PLAP-IN-1 is a selective PLAP inhibitor with an IC50 of 0.032 μM. PLAP-IN-1 acts as a tumor-targeting agent; its fluorescein-conjugated derivative specifically binds to PLAP-positive tumor cells in vitro and targets cervical cancer in mouse xenograft models. PLAP-IN-1 can be used in the research of cervical cancer and ovarian cancer.
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- No. CAS: 2857113-78-9
- Fòrmula: C25H21Cl2N3O5
- Peso molecular:514.36
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
PLAP-IN-1 (compound 16) potently inhibits purified PLAP with an IC50 of 32 nM, and exhibits high selectivity toward tissue-nonspecific alkaline phosphatase (TNAP)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2857113-78-9
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Peso molecular 514.36
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Fòrmula C25H21Cl2N3O5
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SMILES
ClC1=C(OC)C(Cl)=CC(C2=CC=CC(C[C@@H](NC(C3=NNC(C4=CC=C(C)O4)=C3)=O)C(O)=O)=C2)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)