EVX1 - even-skipped homeobox 1 Gene

Also Known as EVX-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2128

About EVX1

Cytogenetic location: 7p15.2 Genomic coordinates (GRCh38): 7:27,242,802-27,247,830 (from NCBI)

This gene has 4 transcripts (splice variants), 195 orthologues and 50 paralogues. Biased expression in prostate (RPKM 2.2), adrenal (RPKM 1.7) and 3 other tissues.

Summary

This gene encodes a member of the even-skipped homeobox family characterized by the presence of a homeodomain closely related to the Drosophila even-skipped (eve) segmentation gene of the pair-rule class. The encoded protein may play an important role as a transcriptional repressor during embryogenesis. [provided by RefSeq, Jul 2008]

EVX1 Products (3)

mRNA Protein Name
NM_001304519.2 NP_001291448.1 homeobox even-skipped homolog protein 1 isoform 2
NM_001304520.2 NP_001291449.1 homeobox even-skipped homolog protein 1 isoform 2
NM_001989.5 NP_001980.1 homeobox even-skipped homolog protein 1 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Referencias Source
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EVX1 Protein Structure

Homeobox

Homeobox: Homeobox domain (184 - 240)

  • 0
  • 100
  • 200
  • 300
  • 407 a.a.
Protein Preferred Names Protein Names

homeobox even-skipped homolog protein 1

  • eve, even-skipped homeo box homolog 1

Related Diseases

Diseases Alias
Hand-Foot-Genital Syndrome

  • Hand-Foot-Uterus Syndrome

  • Hfgs

  • Hfg Syndrome

  • Hfu Syndrome

  • HFG

  • Hfu

  • Hand Foot Uterus Syndrome

  • Hand Foot Genital Syndrome
Preaxial Deficiency, Postaxial Polydactyly, And Hypospadias

  • Guttmacher Syndrome

  • Preaxial Deficiency, Postaxial Polydactyly And Hypospadias

  • Autosomal Dominant Preaxial Deficiency, Postaxial Polydactyly, And Hypospadias

  • Preaxial Deficiency-Postaxial Polydactyly-Hypospadias Syndrome

  • GUTTS
Cervical Incompetence

  • Uterine Cervical Incompetence
Congenital Central Hypoventilation Syndrome

  • Cchs

  • Haddad Syndrome

  • Ondine Curse

  • Ondine Syndrome

  • Congenital Central Hypoventilation

  • Congenital Central Alveolar Hypoventilation Syndrome

  • Congenital Failure Of Autonomic Control

  • Ondine'S Curse

  • Primary Alveolar Hypoventilation

  • Ondine-Hirschsprung Disease

  • Central Congenital Hypoventilation Syndrome

  • Congenital Ondine Curse

  • Idiopathic Congenital Central Alveolar Hypoventilation

  • Congenital Central Alveolar Hypoventilation-Hirschsprung Disease Syndrome

  • Ondine-Hirschsprung Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS04579 EVX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20730 Evx1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27242 Evx1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus EVX1 VGNC VGNC:28637
Canis familiaris EVX1 VGNC VGNC:40506
Rattus norvegicus EVX1 RGD RGD:11434685
Felis catus EVX1 VGNC VGNC:61992
Macaca mulatta EVX1 VGNC VGNC:108403
Mus musculus EVX1 MGD MGI:95461
Others EVX1 NCBI