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Inbakicept

2 Cited Publications
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Based on 2 publication(s) in Google Scholar

Inbakicept is a dimeric human IL-15 receptor alpha (IL-15 Ra) sushi domain/human IgG1 Fc fusion protein and is an IL-15 superagonist complex. Inbakicept is able to form complex N-803 (Nogapendekin alfa inbakicept) with the IL-15 antibody Nogapendekin alfa in a 1:2 ratio. N-803 mimics the function of IL-15 and amplifies anti-CD20 mAb-mediated NK cell responses and antibody-dependent cellular cytotoxicity (ADCC). N-803 also increases degranulation and IFNγ production in cells.

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  • Pureza: ≥99.0%
  • No. CAS: 2135939-52-3
  • Peso molecular:66.58 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Inbakicept
  • Experimental Validation Results for Inbakicept
  • Inbakicept Chemical Structure
    Inbakicept Chemical Structure
No. CAS: 2135939-52-3
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609-228-6898
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Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    [IL15RA (interleukin 15 receptor subunit alpha, CD215, IL-15RA)]2-IGHG1 Fc (Fragment constant)

  • 1/16

    Immobilized Human IL-15 Protein can bind Inbakicept. The EC50 for this effect is 50.78 ng/mL.

  • Inbakicept Chemical Structure
    1/16
  • Inbakicept
  • Immobilized Human IL-15 Protein can bind Inbakicept. The EC50 for this effect is 50.78 ng/mL.
  • [IL15RA (interleukin 15 receptor subunit alpha, CD215, IL-15RA)]2-IGHG1 Fc (Fragment constant)