PALLD - Palld palladin, cytoskeletal associated protein Gene

Rattus norvegicus

Also known as Palldl1; AABR07025295.1

Gene ID: 100360205 | Gene type: protein coding

About PALLD

Summary

Enables cytoskeletal protein binding activity. Involved in several processes, including plasma membrane bounded cell projection organization; positive regulation of podosome assembly; and trophoblast giant cell differentiation. Located in several cellular components, including Z disc; actin cytoskeleton; and axonal growth cone. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human PALLD (palladin, cytoskeletal associated protein). [provided by Alliance of Genome Resources, Apr 2022]

PALLD Products(6)

mRNA	Protein	Name
XM_039094916.1	XP_038950844.1	palladin isoform X3
XM_039094914.1	XP_038950842.1	palladin isoform X1
XM_039094915.1	XP_038950843.1	palladin isoform X2
XM_039094917.1	XP_038950845.1	palladin isoform X4
XM_008771231.3	XP_008769453.1	palladin isoform X5
XM_008771232.3	XP_008769454.1	palladin isoform X6

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables cytoskeletal protein binding	IPI IPI: Inferred from physical interaction	23546604	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to hypoxia	IEP IEP: Inferred from expression pattern	16481593	RGD
involved in neuron projection development	IMP IMP: Inferred from mutant phenotype	12932445	RGD
involved in positive regulation of podosome assembly	IMP IMP: Inferred from mutant phenotype	16868024	RGD
involved in ruffle organization	IMP IMP: Inferred from mutant phenotype	16868024	RGD
involved in trophoblast giant cell differentiation	IEP IEP: Inferred from expression pattern	16481593	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in Z disc	IDA IDA: Inferred from direct assay	11553711	RGD
located in axon	IDA IDA: Inferred from direct assay	11438925	RGD
located in axonal growth cone	IDA IDA: Inferred from direct assay	12932445	RGD
located in cytoskeleton	IDA IDA: Inferred from direct assay	16125169	RGD
located in excitatory synapse	IDA IDA: Inferred from direct assay	11438925	RGD
located in filopodium	IDA IDA: Inferred from direct assay	12932445	RGD
located in growth cone	IDA IDA: Inferred from direct assay	11438925	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	12932445	RGD
located in podosome	IDA IDA: Inferred from direct assay	16868024	RGD
located in ruffle	IDA IDA: Inferred from direct assay	16868024	RGD
located in stress fiber	IDA IDA: Inferred from direct assay	16125169	RGD
located in stress fiber	IMP IMP: Inferred from mutant phenotype	11553711	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

palladin

palladin, cytoskeletal associated protein

palladin-like

palladin-like 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10004	PALLD Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	PALLD	NCBI	NCBI:23022

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