OCA2 - Oca2 OCA2 melanosomal transmembrane protein Gene

About OCA2

Summary

Predicted to be involved in melanin biosynthetic process and melanocyte differentiation. Predicted to act upstream of or within cell population proliferation; developmental pigmentation; and spermatid development. Predicted to be located in endoplasmic reticulum membrane; endosome membrane; and lysosomal membrane. Predicted to be active in melanosome membrane. Human ortholog(s) of this gene implicated in actinic keratosis; oculocutaneous albinism type II; pigmentation disease; skin Cancer (multiple); and squamous cell carcinoma. Orthologous to human OCA2 (OCA2 melanosomal transmembrane protein). [provided by Alliance of Genome Resources, Apr 2022]