Pifo - primary cilia formation Gene

Also Known as 1700027A23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 100503311

Summary

Enables cytoskeletal protein binding activity and enzyme binding activity. Involved in regulation of cell projection organization. Acts upstream of or within with a positive effect on cilium organization. Acts upstream of or within embryonic heart tube left/right pattern formation. Located in ciliary basal body; nucleus; and trans-Golgi network. Is expressed in several structures, including brain ventricle and choroid plexus; embryo ectoderm; lung mesenchyme; node; and testis. Orthologous to human PIFO (primary cilia formation). [provided by Alliance of Genome Resources, Apr 2022]

Pifo Products (2)

mRNA Protein Name
NM_001200028.1 NP_001186957.1 protein pitchfork isoform a
NM_029604.3 NP_083880.2 protein pitchfork isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables beta-tubulin binding IDA
IDA: Inferred from direct assay
20643351 MGI
enables gamma-tubulin binding IDA
IDA: Inferred from direct assay
20643351 MGI
enables kinesin binding IPI
IPI: Inferred from physical interaction
20643351 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20643351 MGI
enables protein kinase binding IPI
IPI: Inferred from physical interaction
20643351 MGI
enables small GTPase binding IPI
IPI: Inferred from physical interaction
20643351 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive effect cilium organization IMP
IMP: Inferred from mutant phenotype
20643351 MGI
acts upstream of or within embryonic heart tube left/right pattern formation IMP
IMP: Inferred from mutant phenotype
20643351 MGI
involved in regulation of cell projection organization IMP
IMP: Inferred from mutant phenotype
20643351 MGI
Cellular Component GO Annotation Evidence References Source
located in ciliary basal body IDA
IDA: Inferred from direct assay
20643351 MGI
located in nucleus IDA
IDA: Inferred from direct assay
20643351 MGI
located in trans-Golgi network IDA
IDA: Inferred from direct assay
20643351 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein pitchfork

  • pitchfork

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10486 PIFO Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pifo NCBI NCBI:128344