Cbarp - calcium channel, voltage-dependent, beta subunit associated regulatory protein Gene

Also Known as Dos; R29144/1; 9630008F14

Species: Mus musculus

Gene Type: protein coding
Gene ID: 100503659

Summary

Enables transmembrane transporter binding activity. Involved in negative regulation of calcium ion-dependent exocytosis and negative regulation of voltage-gated Calcium Channel activity. Located in plasma membrane and secretory granule. Colocalizes with growth cone. Is expressed in nervous system. Orthologous to human CBARP (CACN subunit beta associated regulatory protein). [provided by Alliance of Genome Resources, Apr 2022]

Cbarp Products (1)

mRNA Protein Name
NM_001195268.1 NP_001182197.1 voltage-dependent calcium channel beta subunit-associated regulatory protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables transmembrane transporter binding IDA
IDA: Inferred from direct assay
24751537 MGI
enables transmembrane transporter binding IPI
IPI: Inferred from physical interaction
24751537 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of calcium ion transmembrane transport IMP
IMP: Inferred from mutant phenotype
24751537 MGI
involved in negative regulation of calcium ion-dependent exocytosis IMP
IMP: Inferred from mutant phenotype
24751537 MGI
involved in negative regulation of voltage-gated calcium channel activity IMP
IMP: Inferred from mutant phenotype
24751537 MGI
Cellular Component GO Annotation Evidence References Source
colocalizes with growth cone IDA
IDA: Inferred from direct assay
24751537 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
24751537 MGI
located in secretory granule IDA
IDA: Inferred from direct assay
24751537 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

voltage-dependent calcium channel beta subunit-associated regulatory protein

  • downstream of Stk11 protein

  • protein Dos

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01992 CBARP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cbarp NCBI NCBI:255057