Cbarp - calcium channel, voltage-dependent, beta subunit associated regulatory protein Gene

Mus musculus

Also known as Dos; R29144/1; 9630008F14

Gene ID: 100503659 | Gene type: protein coding

About Cbarp

Summary

Enables transmembrane transporter binding activity. Involved in negative regulation of calcium ion-dependent exocytosis and negative regulation of voltage-gated Calcium Channel activity. Located in plasma membrane and secretory granule. Colocalizes with growth cone. Is expressed in nervous system. Orthologous to human CBARP (CACN subunit beta associated regulatory protein). [provided by Alliance of Genome Resources, Apr 2022]

Cbarp Products(1)

mRNA	Protein	Name
NM_001195268.1	NP_001182197.1	voltage-dependent calcium channel beta subunit-associated regulatory protein

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables transmembrane transporter binding	IDA IDA: Inferred from direct assay	24751537	MGI
enables transmembrane transporter binding	IPI IPI: Inferred from physical interaction	24751537	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of calcium ion transmembrane transport	IMP IMP: Inferred from mutant phenotype	24751537	MGI
involved in negative regulation of calcium ion-dependent exocytosis	IMP IMP: Inferred from mutant phenotype	24751537	MGI
involved in negative regulation of voltage-gated calcium channel activity	IMP IMP: Inferred from mutant phenotype	24751537	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
colocalizes with growth cone	IDA IDA: Inferred from direct assay	24751537	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	24751537	MGI
located in secretory granule	IDA IDA: Inferred from direct assay	24751537	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

voltage-dependent calcium channel beta subunit-associated regulatory protein

downstream of Stk11 protein

protein Dos

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01992	CBARP Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cbarp	NCBI	NCBI:255057

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