Derl2 - derlin 2 Gene

Predicted to enable signal recognition particle binding activity. Predicted to be involved in several processes, including endoplasmic reticulum unfolded protein response; negative regulation of retrograde protein transport, ER to cytosol; and ubiquitin-dependent ERAD pathway. Predicted to act upstream of or within retrograde protein transport, ER to cytosol and suckling behavior. Predicted to be located in early endosome; endoplasmic reticulum; and late endosome. Predicted to be integral component of endoplasmic reticulum membrane. Orthologous to human DERL2 (derlin 2). [provided by Alliance of Genome Resources, Apr 2022]