PRSS16 - serine protease 16 Gene

Also Known as TSSP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10279

About PRSS16

Cytogenetic location: 6p22.1 Genomic coordinates (GRCh38): 6:27,247,701-27,256,620 (from NCBI)

This gene has 20 transcripts (splice variants), 206 orthologues and 2 paralogues. Broad expression in thyroid (RPKM 6.8), stomach (RPKM 3.4) and 17 other tissues.

Summary

This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]

PRSS16 Products (1)

mRNA Protein Name
NM_005865.4 NP_005856.1 thymus-specific serine protease

PRSS16 Protein Structure

Peptidase_S28

Peptidase_S28: Serine carboxypeptidase S28 (64 - 494)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 514 a.a.
Protein Preferred Names Protein Names

thymus-specific serine protease

  • protease, serine 16

Related Diseases

Diseases Alias
Capillariasis

  • Capillaria Infection

  • Enoplida Infections

  • Capillariasis Nos

  • Capillariosis
Pulmonary Embolism And Infarction
Sparganosis

  • Infection By Sparganum

  • Larval Diphyllobothriasis

  • Spirometrosis

  • Infection By Spirometra Larvae

  • Larval Dibothriocephaliasis

  • Sparganosis - Larval Diphyllobothriasis

  • Spirometriosis

  • Larval Dibothriocephalus Infestation

  • Larval Diphyllobothrium Infestation

  • Larval Dibothriocephalus

  • Infection Due To Sparganum

  • Larval Fish Tapeworm Infection

  • Spirometra Larvae Infestation

  • Sparganum Infestation

  • Larval Bothriocephalus Infestation
T-Cell Immunodeficiency With Thymic Aplasia

  • Nezelof Syndrome

  • T-Lymphocyte Deficiency

  • TIDTA

  • Immune Defect Due To Absence Of Thymus

  • Thymic Aplasia

  • Nezelof'S Syndrome

  • Thymic Dysplasia With Normal Immunoglobulins

  • Thymic Aplasia Syndrome

  • T-Lymphocyte Immunodeficiency
Thymic Dysplasia
Paragonimiasis

  • Infection By Paragonimus

  • Lung Fluke Disease

  • Lung Fluke Infection

  • Pulmonary Paragonimiasis

  • Paragonimus Westermani Infection

  • Pulmonary Distomiasis

  • Parasitic Haemoptysis

  • Oriental Lung Fluke Disease

  • Endemic Haemoptysis

  • Paragonimosis

  • Pulmonary Distomatosis

  • Lung Fluke Disorder

  • Infestation By Paragonimus

  • Infection Due To Paragonimus Species

  • Infestation Due To Paragonimus Species

  • Oriental Lung Fluke Infestation

  • Endemic Oriental Haemoptysis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11247 PRSS16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus PRSS16 MGD MGI:1859181
Bos taurus PRSS16 VGNC VGNC:33414
Canis familiaris PRSS16 VGNC VGNC:45063
Rattus norvegicus PRSS16 RGD RGD:1306652
Felis catus PRSS16 VGNC VGNC:69090
Macaca mulatta PRSS16 VGNC VGNC:82214
Others PRSS16 NCBI