Smg6 - SMG6 nonsense mediated mRNA decay factor Gene

Mus musculus

Gene ID: 103677 | Gene type: protein coding

About Smg6

Summary

Predicted to enable several functions, including DNA Polymerase binding activity; endoribonuclease activity; and nucleic acid binding activity. Predicted to be involved in negative regulation of telomere capping and nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to be located in cytosol and nucleolus. Predicted to be part of exon-exon junction complex and Telomerase holoenzyme complex. Orthologous to human SMG6 (SMG6 nonsense mediated mRNA decay factor). [provided by Alliance of Genome Resources, Apr 2022]

Smg6 Products(1)

mRNA	Protein	Name
NM_001002764.2	NP_001002764.1	telomerase-binding protein EST1A

Protein Preferred Names

Protein Names

telomerase-binding protein EST1A

EST1-like protein A	Smg-6 homolog, nonsense mediated mRNA decay factor
ever shorter telomeres 1A	nonsense mediated mRNA decay factor SMG6
telomerase subunit EST1A

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13432	SMG6 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Smg6	NCBI	NCBI:23293

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