2. Gene
  3. Synpo - synaptopodin Gene

Synpo - synaptopodin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 9130229N11; 9030217H17Rik; 9330140I15Rik

Gene ID: 104027 | Gene type: protein coding

About Synpo

Summary

Enables actin binding activity. Involved in several processes, including modulation of chemical synaptic transmission; regulation of actin filament bundle assembly; and spine apparatus assembly. Located in several cellular components, including Schaffer collateral - CA1 synapse; spine apparatus; and stress fiber. Is active in glutamatergic synapse. Is expressed in several structures, including genitourinary system; respiratory system; sensory organ; skeleton; and tooth. Orthologous to human SYNPO (synaptopodin). [provided by Alliance of Genome Resources, Apr 2022]

Synpo Products(2)

mRNA Protein Name
NM_001109975.1 NP_001103445.1 synaptopodin isoform B
NM_177340.2 NP_796314.2 synaptopodin isoform A
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables actin binding IDA
IDA: Inferred from direct assay
9314539 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
37651441 MGI
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of actin filament bundle assembly IDA
IDA: Inferred from direct assay
15841212 MGI
involved in postsynaptic modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
12928494 MGI
involved in postsynaptic modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
12928494 MGI
involved in regulation of long-term neuronal synaptic plasticity IMP
IMP: Inferred from mutant phenotype
12928494 MGI
involved in regulation of postsynaptic cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
25164660 MGI
involved in regulation of postsynaptic cytosolic calcium ion concentration IMP
IMP: Inferred from mutant phenotype
25164660 MGI
involved in regulation of stress fiber assembly IDA
IDA: Inferred from direct assay
15841212 MGI
involved in spine apparatus assembly IMP
IMP: Inferred from mutant phenotype
12928494 MGI
involved in visual learning IMP
IMP: Inferred from mutant phenotype
12928494 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
12928494 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: Inferred from mutant phenotype
12928494 MGI
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
9314539 MGI
located in cell periphery IDA
IDA: Inferred from direct assay
25071083 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
12928494 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
12928494 MGI
located in stress fiber IDA
IDA: Inferred from direct assay
15841212 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synaptopodin

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14097 SYNPO Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14098 SYNPO2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14099 SYNPO2L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Synpo NCBI NCBI:11346