Dph3 - diphthamine biosynthesis 3 Gene

Also Known as Desr1; KTI11; Zcsl2; DELGIP1; DelgipP1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 105638

Summary

Predicted to enable metal ion binding activity. Predicted to be involved in peptidyl-diphthamide biosynthetic process from peptidyl-histidine and tRNA wobble uridine modification. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in cytosol and nucleus. Orthologous to several human genes including DPH3 (diphthamide biosynthesis 3). [provided by Alliance of Genome Resources, Apr 2022]

Dph3 Products (3)

mRNA Protein Name
NM_001047433.2 NP_001040898.1 diphthamide biosynthesis protein 3 isoform 2
NM_001284346.1 NP_001271275.1 diphthamide biosynthesis protein 3 isoform 1
NM_172254.4 NP_758458.1 diphthamide biosynthesis protein 3 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in protein histidyl modification to diphthamide IMP
IMP: Inferred from mutant phenotype
16648478 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

diphthamide biosynthesis protein 3

  • CSL-type zinc finger-containing protein 2

  • DPH3 homolog (KTI11, S. cerevisiae)

  • delGEF-interacting protein 1

  • zinc finger, CSL domain containing 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03954 DPH3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dph3 NCBI NCBI:285381