1. Gene
  2. Thtpa - thiamine triphosphatase Gene

Thtpa - thiamine triphosphatase Gene

Mus musculus
Gene ID: 105663 | Gene type: protein coding

About Thtpa

Summary

This gene encodes a cytosolic enzyme that catalyzes the conversion of thiamine triphosphate to thiamine diphosphate. The encoded protein requires divalent cations for enzymatic activity. The gene product is believed to play a role in regulation of thiamine triphosphate intracellular concentration, and it may be a messenger in cell signaling in response to cellular stress. [provided by RefSeq, Mar 2010]

Thtpa Products(1)

mRNA Protein Name
NM_153083.5 NP_694723.1 thiamine-triphosphatase
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables magnesium ion binding IDA
IDA: Inferred from direct assay
18276586 MGI
enables thiamine triphosphate phosphatase activity IDA
IDA: Inferred from direct assay
18276586 MGI
Biological Process GO Annotation Evidence Reference Source
involved in thiamine diphosphate biosynthetic process IDA
IDA: Inferred from direct assay
18276586 MGI
involved in thiamine diphosphate metabolic process IDA
IDA: Inferred from direct assay
18276586 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in cytosol IDA
IDA: Inferred from direct assay
18276586 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thiamine-triphosphatase

ThTPase

Orthologs Information

Species Symbol Source ID
Homo sapiens Thtpa NCBI NCBI:79178