2. Gene
  3. Dnah1 - dynein, axonemal, heavy chain 1 Gene

Dnah1 - dynein, axonemal, heavy chain 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as MDHC7; ferf1; Dnahc1; G1-415-19; B230373P09Rik; E030034C22Rik

Gene ID: 110084 | Gene type: protein coding

About Dnah1

Summary

Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Acts upstream of or within epithelial cilium movement involved in extracellular fluid movement and flagellated sperm motility. Located in sperm flagellum. Is expressed in cerebellum; choroid plexus; and lateral ventricle choroid plexus. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 37 and spermatogenic failure 18. Orthologous to human DNAH1 (dynein axonemal heavy chain 1). [provided by Alliance of Genome Resources, Apr 2022]

Dnah1 Products(1)

mRNA Protein Name
NM_001033668.1 NP_001028840.1 dynein axonemal heavy chain 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cilium movement involved in cell motility IMP
IMP: Inferred from mutant phenotype
11371505 MGI
acts upstream of or within epithelial cilium movement involved in extracellular fluid movement IMP
IMP: Inferred from mutant phenotype
11371505 MGI
acts upstream of or within flagellated sperm motility IMP
IMP: Inferred from mutant phenotype
11371505 MGI
Cellular Component GO Annotation Evidence Reference Source
located in sperm flagellum IDA
IDA: Inferred from direct assay
11371505 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dynein axonemal heavy chain 1

dynein heavy chain 1, axonemal

axonemal beta dynein heavy chain 1

ciliary dynein heavy chain 1

dynein, axon, heavy chain 1

dynein, axonemal, heavy polypeptide 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03842 DNAH1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dnah1 NCBI NCBI:25981