2. Gene
  3. C8b - complement component 8, beta polypeptide Gene

C8b - complement component 8, beta polypeptide Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 4930439B20Rik

Gene ID: 110382 | Gene type: protein coding

About C8b

Summary

This gene encodes the beta subunit of complement component C8 that participates in the assembly of the complement membrane attack complex. The encoded preproprotein undergoes proteolytic processing to generate the beta subunit, which associates with the alpha and gamma subunits to form a trimeric complement component, C8. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. This gene is located adjacent to the gene encoding the alpha subunit. [provided by RefSeq, Oct 2015]

C8b Products(2)

mRNA Protein Name
NM_001316671.1 NP_001303600.1 complement component C8 beta chain isoform 2 precursor
NM_133882.2 NP_598643.1 complement component C8 beta chain isoform 1 preproprotein
Protein Preferred Names Protein Names

complement component C8 beta chain

complement component 8, beta subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01756 C8B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens C8b NCBI NCBI:732