ADAM29 - ADAM metallopeptidase domain 29 Gene
Also Known as CT73; svph1
Species: Homo sapiens
About ADAM29
This gene has 14 transcripts (splice variants), 416 orthologues and 20 paralogues. Restricted expression toward testis (RPKM 20.8).
Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is highly expressed in testis and may be involved in human spermatogenesis. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
ADAM29 Products (7)
| mRNA | Protein | Name |
|---|---|---|
| NM_001130703.1 | NP_001124175.1 | disintegrin and metalloproteinase domain-containing protein 29 preproprotein |
| NM_001130704.1 | NP_001124176.1 | disintegrin and metalloproteinase domain-containing protein 29 preproprotein |
| NM_001130705.1 | NP_001124177.1 | disintegrin and metalloproteinase domain-containing protein 29 preproprotein |
| NM_001278125.1 | NP_001265054.1 | disintegrin and metalloproteinase domain-containing protein 29 preproprotein |
| NM_001278126.1 | NP_001265055.1 | disintegrin and metalloproteinase domain-containing protein 29 preproprotein |
| NM_001278127.1 | NP_001265056.1 | disintegrin and metalloproteinase domain-containing protein 29 preproprotein |
| NM_014269.4 | NP_055084.3 | disintegrin and metalloproteinase domain-containing protein 29 preproprotein |
ADAM29 Protein Structure
Pep_M12B_propep: Reprolysin family propeptide (32 - 150)
Reprolysin: Reprolysin (M12B) family zinc metalloprotease (198 - 387)
Disintegrin: Disintegrin (406 - 480)
ADAM_CR: ADAM cysteine-rich (483 - 598)
- 0
- 200
- 400
- 600
- 820 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
disintegrin and metalloproteinase domain-containing protein 29 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Melanoma |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Canis familiaris | ADAM29 | VGNC | VGNC:37583 |
| Rattus norvegicus | ADAM29 | RGD | RGD:1309066 |
| Mus musculus | ADAM29 | MGD | MGI:2676326 |
| Macaca mulatta | ADAM29 | VGNC | VGNC:106537 |
| Others | ADAM29 | NCBI |