Chrna2 - cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) Gene

Predicted to enable acetylcholine-gated cation-selective channel activity. Predicted to contribute to acetylcholine receptor activity. Predicted to be involved in several processes, including cholinergic synaptic transmission; regulation of membrane potential; and response to nicotine. Located in cell periphery. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and spinal cord. Human ortholog(s) of this gene implicated in autosomal dominant nocturnal frontal lobe epilepsy 4. Orthologous to human CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit). [provided by Alliance of Genome Resources, Apr 2022]