Chrna2 - cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) Gene

Mus musculus

Also known as Acra2; Acra-2

Gene ID: 110902 | Gene type: protein coding

About Chrna2

Summary

Predicted to enable acetylcholine-gated cation-selective channel activity. Predicted to contribute to acetylcholine receptor activity. Predicted to be involved in several processes, including cholinergic synaptic transmission; regulation of membrane potential; and response to nicotine. Located in cell periphery. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and spinal cord. Human ortholog(s) of this gene implicated in autosomal dominant nocturnal frontal lobe epilepsy 4. Orthologous to human CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit). [provided by Alliance of Genome Resources, Apr 2022]

Chrna2 Products(1)

mRNA	Protein	Name
NM_144803.2	NP_659052.1	neuronal acetylcholine receptor subunit alpha-2 precursor

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
located in cell periphery	IDA IDA: Inferred from direct assay	21884692	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

neuronal acetylcholine receptor subunit alpha-2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02667	CHRNA2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Chrna2	NCBI	NCBI:1135

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