PXMP4 - peroxisomal membrane protein 4 Gene

Also Known as PMP24

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 11264

About PXMP4

Cytogenetic location: 20q11.22 Genomic coordinates (GRCh38): 20:33,702,758-33,720,310 (from NCBI)

This gene has 3 transcripts (splice variants) and 200 orthologues. Ubiquitous expression in lung (RPKM 6.4), thyroid (RPKM 4.6) and 25 other tissues.

Summary

Located in peroxisomal membrane. [provided by Alliance of Genome Resources, Apr 2022]

PXMP4 Products (2)

mRNA Protein Name
NM_007238.5 NP_009169.3 peroxisomal membrane protein 4 isoform a
NM_183397.3 NP_899634.1 peroxisomal membrane protein 4 isoform b

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
14709540 GOA
Cellular Component GO Annotation Evidence References Source
located in peroxisomal membrane IDA
IDA: Inferred from direct assay
14709540 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PXMP4 Protein Structure

Tim17

Tim17: Tim17/Tim22/Tim23/Pmp24 family (23 - 145)

  • 0
  • 100
  • 200
  • 212 a.a.
Protein Preferred Names Protein Names

peroxisomal membrane protein 4

  • 24 kDa peroxisomal intrinsic membrane protein

Related Diseases

Diseases Alias
Alpha-Methylacyl-Coa Racemase Deficiency

  • Amacr Deficiency

  • AMACRD
Peroxisomal Biogenesis Disorder

  • Zellweger Spectrum Disorders

  • Peroxisome Biogenesis Disorder-Zellweger Syndrome Spectrum

  • Disorders Of Peroxisome Biogenesis

  • Zellweger Spectrum

  • Zellweger Syndrome Spectrum

  • Peroxisomal Biogenesis Disorders

  • Pbd, Zss

  • Pbd-Zsd

  • Pbd-Zss

  • Pbd-Zellweger Spectrum Disorder

  • Peroxisomal Biogenesis Disorders, Zellweger Syndrome Spectrum

  • Peroxisome Biogenesis Disorder

  • Peroxisome Biogenesis Disorder Spectrum

  • Peroxisome Biogenesis Disorders

  • Zellweger Spectrum Disorder

  • Hyperpipecolic Acidaemia
Zellweger Syndrome

  • Cerebrohepatorenal Syndrome

  • Zellweger Leukodystrophy

  • Zs

  • Congenital Iron Overload

  • Chr

  • Zws

  • Severe Pbd-Zsd

  • Severe Peroxisome Biogenesis Disorder-Zellweger Spectrum Disorder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11483 PXMP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus PXMP4 VGNC VGNC:33585
Mus musculus PXMP4 MGD MGI:1891701
Macaca mulatta PXMP4 VGNC VGNC:97125
Felis catus PXMP4 VGNC VGNC:64449
Canis familiaris PXMP4 VGNC VGNC:45221
Rattus norvegicus PXMP4 RGD RGD:628782
Others PXMP4 NCBI