RIMS2 - Rims2 regulating synaptic membrane exocytosis 2 Gene

Also Known as Nim2; Rim2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 116839

Summary

Enables protein domain specific binding activity. Predicted to be involved in several processes, including cAMP-mediated signaling; modulation of chemical synaptic transmission; and signal release. Predicted to act upstream of or within adenylate cyclase-modulating G protein-coupled receptor signaling pathway and neurotransmitter secretion. Located in synapse. Part of protein-containing complex. Is active in photoreceptor ribbon synapse and presynaptic active zone cytoplasmic component. Orthologous to human RIMS2 (regulating synaptic membrane exocytosis 2). [provided by Alliance of Genome Resources, Apr 2022]

RIMS2 Products (2)

mRNA Protein Name
NM_053945.2 NP_446397.1 regulating synaptic membrane exocytosis protein 2 isoform 1
NM_145881.2 NP_665888.1 regulating synaptic membrane exocytosis protein 2 isoform 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11797009 RGD
enables protein domain specific binding IDA
IDA: Inferred from direct assay
16732694 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
16732694 RGD
Cellular Component GO Annotation Evidence References Source
is active in photoreceptor ribbon synapse IDA
IDA: Inferred from direct assay
9252191 RGD
is active in presynaptic active zone cytoplasmic component IDA
IDA: Inferred from direct assay
9252191 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
16732694 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

regulating synaptic membrane exocytosis protein 2

  • RIM 2

  • rab-3-interacting molecule 2

  • rab3-interacting molecule 2

  • regulating synaptic membrane exocytosis protein 2-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11979 RIMS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21733 Rims2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28250 Rims2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens RIMS2 NCBI NCBI:9699