WDR17 - WD repeat domain 17 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 116966

About WDR17

Cytogenetic location: 4q34.2 Genomic coordinates (GRCh38): 4:176,065,841-176,182,815 (from NCBI)

This gene has 8 transcripts (splice variants), 205 orthologues and 26 paralogues. Biased expression in brain (RPKM 5.2), thyroid (RPKM 2.5) and 12 other tissues.

Summary

This gene encodes a WD repeat-containing protein. It is abundantly expressed in retina and testis, and is thought to be a candidate gene for retinal disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2009]

WDR17 Products (7)

mRNA Protein Name
NM_001350727.2 NP_001337656.1 WD repeat-containing protein 17 isoform 3
NM_001378103.1 NP_001365032.1 WD repeat-containing protein 17 isoform 4
NM_001378104.1 NP_001365033.1 WD repeat-containing protein 17 isoform 5
NM_001378105.1 NP_001365034.1 WD repeat-containing protein 17 isoform 6
NM_001378106.1 NP_001365035.1 WD repeat-containing protein 17 isoform 7
NM_170710.5 NP_733828.2 WD repeat-containing protein 17 isoform 1
NM_181265.4 NP_851782.3 WD repeat-containing protein 17 isoform 2

WDR17 Protein Structure

WD40

WD40: WD domain, G-beta repeat (75 - 112)

WD40

WD40: WD domain, G-beta repeat (391 - 422)

WD40

WD40: WD domain, G-beta repeat (477 - 505)

WD40

WD40: WD domain, G-beta repeat (518 - 549)

WD40

WD40: WD domain, G-beta repeat (557 - 595)

WD40

WD40: WD domain, G-beta repeat (601 - 638)

WD40

WD40: WD domain, G-beta repeat (642 - 681)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1322 a.a.
Protein Preferred Names Protein Names

WD repeat-containing protein 17

  • epididymis secretory sperm binding protein

Related Diseases

Diseases Alias
Anal Squamous Cell Carcinoma

  • Epidermoid Anal Carcinoma

  • Carcinoma Of Anal Margin
Retinal Disease

  • Retinal Diseases

  • Retinal Disorder

  • Retinal Disorders
Retinitis Pigmentosa 29

  • RP29
Anus Cancer

  • Anal Cancer

  • Anal Carcinoma

  • Malignant Anal Tumor

  • Cancer Of The Anus

  • Malignant Neoplasm Of Anus

  • Anus Neoplasms
Retinitis Pigmentosa

  • RP

  • Rod-Cone Dystrophy

  • Autosomal Recessive Retinitis Pigmentosa

  • Non-Syndromic Retinitis Pigmentosa

  • Pericentral Pigmentary Retinopathy

  • Pigmentary Retinopathy

  • Tapetoretinal Degeneration

  • Rcd

  • Retinitis Pigmentosa Autosomal Recessive

  • ARRP

  • Retinitis Pigmentosa, Autosomal Recessive

  • Retinitis Pigmentosa 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15764 WDR17 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus WDR17 VGNC VGNC:36884
Mus musculus WDR17 MGD MGI:1924662
Canis familiaris WDR17 VGNC VGNC:48353
Felis catus WDR17 VGNC VGNC:67017
Macaca mulatta WDR17 VGNC VGNC:100287
Rattus norvegicus WDR17 RGD RGD:1590843
Others WDR17 NCBI