Hnrnpu - heterogeneous nuclear ribonucleoprotein U Gene

Also Known as SN1; Hnrpu; SAF-A; SP120; hnRNP U

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117280

Summary

Enables poly(G) binding activity; promoter-specific chromatin binding activity; and ribonucleoprotein complex binding activity. Involved in cellular response to dexamethasone stimulus; positive regulation of DNA Topoisomerase (ATP-hydrolyzing) activity; and positive regulation of gene expression. Located in nucleus. Part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 54. Orthologous to human HNRNPU (heterogeneous nuclear ribonucleoprotein U). [provided by Alliance of Genome Resources, Apr 2022]

Hnrnpu Products (1)

mRNA Protein Name
NM_057139.2 NP_476480.2 heterogeneous nuclear ribonucleoprotein U

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
20554522 RGD
enables poly(G) binding IDA
IDA: Inferred from direct assay
20554522 RGD
enables promoter-specific chromatin binding IDA
IDA: Inferred from direct assay
19632204 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
20554522 RGD
enables ribonucleoprotein complex binding IPI
IPI: Inferred from physical interaction
20554522 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to dexamethasone stimulus IDA
IDA: Inferred from direct assay
19632204 RGD
involved in positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity IDA
IDA: Inferred from direct assay
20554522 RGD
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
20554522 RGD
Cellular Component GO Annotation Evidence References Source
part of ribonucleoprotein complex IDA
IDA: Inferred from direct assay
12855701 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heterogeneous nuclear ribonucleoprotein U

  • scaffold-attachment factor A

  • system N1 Na+ and H+-coupled glutamine transporter

  • transporter protein

  • transporter protein

  • system N1 Na+ and H+-coupled glutamine transporter

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06278 HNRNPU Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21138 Hnrnpu Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27656 Hnrnpu Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hnrnpu NCBI NCBI:3192