SPATA4 - spermatogenesis associated 4 Gene

Homo sapiens

Also known as FAP178; SPEF1B; TSARG2; CFAP178

Gene ID: 132851 | Gene type: protein coding

About SPATA4

Cytogenetic location: 4q34.2 Genomic coordinates (GRCh38): 4:176,184,579-176,195,585 (from NCBI)

This gene has 3 transcripts (splice variants), 176 orthologues and 1 paralogue. Restricted expression toward testis (RPKM 71.0).

Summary

Predicted to enable microtubule binding activity. Predicted to be involved in regulation of Cytoskeleton organization. Predicted to be located in cytoplasm. Predicted to be active in axoneme. [provided by Alliance of Genome Resources, Apr 2022]

SPATA4 Products(1)

mRNA	Protein	Name
NM_144644.4	NP_653245.2	spermatogenesis-associated protein 4

SPATA4 Protein Structure

CH_2

0
100
200
305 a.a.

Protein Preferred Names

Protein Names

spermatogenesis-associated protein 4

testis and spermatogenesis cell related protein 2

Related Diseases

Diseases

Alias

Hermaphroditism

Cryptorchidism, Unilateral Or Bilateral

Cryptorchidism	Undescended Testicle
Undescended Testis	Cryptorchism
Undescended Testicles	CRYPTO
Impaired Testicular Descent	Cryptosporidiosis
Retained Testis	Unilateral Cryptorchidism
Unilateral Undescended Testis	Nondescent Unilateral Testicle
Unilateral Cryptorchism	Ectopic Testis, Unilateral
Bilateral Cryptorchidism	Bilateral Cryptorchism
Bilateral Nondescent Testicle	Bilateral Undescended Testes
Bilateral Ectopic Testes

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13640	SPATA4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	SPATA4	RGD	RGD:1303065
Canis familiaris	SPATA4	VGNC	VGNC:46714
Bos taurus	SPATA4	VGNC	VGNC:35184
Macaca mulatta	SPATA4	VGNC	VGNC:77938
Mus musculus	SPATA4	MGD	MGI:1916531
Felis catus	SPATA4	VGNC	VGNC:65613

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