SPATA4 - spermatogenesis associated 4 Gene

Also Known as FAP178; SPEF1B; TSARG2; CFAP178

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 132851

About SPATA4

Cytogenetic location: 4q34.2 Genomic coordinates (GRCh38): 4:176,184,579-176,195,585 (from NCBI)

This gene has 3 transcripts (splice variants), 176 orthologues and 1 paralogue. Restricted expression toward testis (RPKM 71.0).

Summary

Predicted to enable microtubule binding activity. Predicted to be involved in regulation of Cytoskeleton organization. Predicted to be located in cytoplasm. Predicted to be active in axoneme. [provided by Alliance of Genome Resources, Apr 2022]

SPATA4 Products (1)

mRNA Protein Name
NM_144644.4 NP_653245.2 spermatogenesis-associated protein 4

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SPATA4 Protein Structure

CH_2

CH_2: CH-like domain in sperm protein (55 - 210)

  • 0
  • 100
  • 200
  • 305 a.a.
Protein Preferred Names Protein Names

spermatogenesis-associated protein 4

  • testis and spermatogenesis cell related protein 2

Related Diseases

Diseases Alias
Hermaphroditism
Cryptorchidism, Unilateral Or Bilateral

  • Cryptorchidism

  • Undescended Testicle

  • Undescended Testis

  • Cryptorchism

  • Undescended Testicles

  • CRYPTO

  • Impaired Testicular Descent

  • Cryptosporidiosis

  • Retained Testis

  • Unilateral Cryptorchidism

  • Unilateral Undescended Testis

  • Nondescent Unilateral Testicle

  • Unilateral Cryptorchism

  • Ectopic Testis, Unilateral

  • Bilateral Cryptorchidism

  • Bilateral Cryptorchism

  • Bilateral Nondescent Testicle

  • Bilateral Undescended Testes

  • Bilateral Ectopic Testes
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13640 SPATA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SPATA4 RGD RGD:1303065
Canis familiaris SPATA4 VGNC VGNC:46714
Bos taurus SPATA4 VGNC VGNC:35184
Macaca mulatta SPATA4 VGNC VGNC:77938
Mus musculus SPATA4 MGD MGI:1916531
Felis catus SPATA4 VGNC VGNC:65613