PASD1 - PAS domain containing repressor 1 Gene

Also Known as CT63; CT64; OXTES1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 139135

About PASD1

Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:151,563,675-151,676,739 (from NCBI)

This gene has 2 transcripts (splice variants), 157 orthologues and 6 paralogues. Restricted expression toward testis (RPKM 11.6).

Summary

This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma. [provided by RefSeq, May 2010]

PASD1 Products (1)

mRNA Protein Name
NM_173493.3 NP_775764.2 circadian clock protein PASD1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor binding IPI
IPI: Inferred from physical interaction
25936801 GOA
enables transcription regulator inhibitor activity IDA
IDA: Inferred from direct assay
25936801 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
25936801 GOA
involved in negative regulation of circadian rhythm IDA
IDA: Inferred from direct assay
25936801 GOA
Cellular Component GO Annotation Evidence References Source
part of Cry-Per complex IDA
IDA: Inferred from direct assay
25936801 GOA
located in nucleus IDA
IDA: Inferred from direct assay
25936801 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

circadian clock protein PASD1

  • PAS domain containing 1

Related Diseases

Diseases Alias
B-Cell Lymphoma

  • Lymphoma, B-Cell

  • B-Cell Lymphomas

  • B-Cell Lymphocytic Neoplasm

  • Lymphoma B-Cell

  • B-Cell Lymphoma Nos
Diffuse Large B-Cell Lymphoma

  • Dlbcl

  • Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

  • Large B-Cell Diffuse Lymphoma

  • Lymphoma, Large B-Cell, Diffuse

  • Dlbcl - [Diffuse Large B-Cell Lymphoma]

  • Diffuse Large Beta Cell Lymphoma
Lymphoma

  • Lymphoid Cancer

  • Lymphomas

  • Lymphoid Cancers

  • Lymphoid Neoplasm

  • Lymphoma Nos

  • Nhl - [Non-Hodgkin Lymphoma]

  • Non-Hodgkin Lymphoma

  • Non-Hodgkin Lymphoma, Nos

  • Non-Hodgkin Malignant Lymphoma Nos
Adult Oligodendroglioma

  • Adult Brain Oligodendroglioma

  • Grade Ii Adult Oligodendroglial Tumor

  • Oligodendroglioma, Adult
Pilocytic Astrocytoma Of Cerebellum

  • Cerebellar Pilocytic Astrocytoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris PASD1 VGNC VGNC:44269
Mus musculus PASD1 MGD MGI:2685987
Macaca mulatta PASD1 VGNC VGNC:75659
Rattus norvegicus PASD1 RGD RGD:7496877
Others PASD1 NCBI