Phkg2 - phosphorylase kinase catalytic subunit gamma 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 140671

Summary

Enables several functions, including ATP binding activity; Calmodulin binding activity; and Phosphorylase kinase activity. Involved in glycogen metabolic process and protein phosphorylation. Part of Phosphorylase kinase complex. Used to study glycogen storage disease. Human ortholog(s) of this gene implicated in glycogen storage disease; glycogen storage disease IXc; and liver cirrhosis. Orthologous to human PHKG2 (Phosphorylase kinase catalytic subunit gamma 2). [provided by Alliance of Genome Resources, Apr 2022]

Phkg2 Products (1)

mRNA Protein Name
NM_080584.4 NP_542151.1 phosphorylase b kinase gamma catalytic chain, liver/testis isoform

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP binding IDA
IDA: Inferred from direct assay
6281247 RGD
enables calmodulin binding IDA
IDA: Inferred from direct assay
1370475 RGD
enables enzyme binding IDA
IDA: Inferred from direct assay
1370475 RGD
enables phosphorylase kinase activity IDA
IDA: Inferred from direct assay
1370475 RGD
Biological Process GO Annotation Evidence References Source
involved in glycogen metabolic process IDA
IDA: Inferred from direct assay
1370475 RGD
involved in positive regulation of glycogen catabolic process IMP
IMP: Inferred from mutant phenotype
6615485 RGD
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
1370475 RGD
Cellular Component GO Annotation Evidence References Source
part of phosphorylase kinase complex IDA
IDA: Inferred from direct assay
6809757 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphorylase b kinase gamma catalytic chain, liver/testis isoform

  • PHK-gamma-LT

  • PHK-gamma-T

  • phosphorylase kinase gamma subunit 2

  • phosphorylase kinase subunit gamma-2

  • phosphorylase kinase, gamma 2 (testis)

  • serine/threonine-protein kinase PHKG2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10441 PHKG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22727 Phkg2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29241 Phkg2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Phkg2 NCBI NCBI:5261