NEURL2 - neuralized E3 ubiquitin protein ligase 2 Gene

Also Known as OZZ; OZZ-E3; C20orf163

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 140825

About NEURL2

Cytogenetic location: 20q13.12 Genomic coordinates (GRCh38): 20:45,888,634-45,891,208 (from NCBI)

This gene has 2 transcripts (splice variants) and 185 orthologues. Ubiquitous expression in kidney (RPKM 2.2), ovary (RPKM 2.0) and 25 other tissues.

Summary

This gene encodes a protein that is involved in the regulation of myofibril organization. This protein is likely the adaptor component of the E3 ubiquitin Ligase complex in striated muscle, and it regulates the ubiquitin-mediated degradation of beta-catenin during myogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2013]

NEURL2 Products (2)

mRNA Protein Name
NM_001278535.2 NP_001265464.1 neuralized-like protein 2 isoform 2
NM_080749.4 NP_542787.1 neuralized-like protein 2 isoform 1

NEURL2 Protein Structure

Neuralized

Neuralized: Neuralized (24 - 90)

SOCS_box

SOCS_box: SOCS box (249 - 285)

  • 0
  • 100
  • 200
  • 285 a.a.
Protein Preferred Names Protein Names

neuralized-like protein 2

  • neuralized homolog 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09221 NEURL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus NEURL2 VGNC VGNC:81131
Bos taurus NEURL2 VGNC VGNC:32015
Canis familiaris NEURL2 VGNC VGNC:43751
Rattus norvegicus NEURL2 RGD RGD:1306409
Mus musculus NEURL2 MGD MGI:3043305
Macaca mulatta NEURL2 VGNC VGNC:107824
Others NEURL2 NCBI