XRRA1 - X-ray radiation resistance associated 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 143570

About XRRA1

Cytogenetic location: 11q13.4 Genomic coordinates (GRCh38): 11:74,840,910-74,949,091 (from NCBI)

This gene has 22 transcripts (splice variants) and 162 orthologues. Broad expression in testis (RPKM 10.6), thyroid (RPKM 6.1) and 25 other tissues.

Summary

Involved in response to X-ray. Located in cytoplasm and nuclear body. [provided by Alliance of Genome Resources, Apr 2022]

XRRA1 Products (23)

mRNA Protein Name
NM_001270380.3 NP_001257309.1 X-ray radiation resistance-associated protein 1 isoform 2
NM_001270381.3 NP_001257310.1 X-ray radiation resistance-associated protein 1 isoform 3
NM_001378157.1 NP_001365086.1 X-ray radiation resistance-associated protein 1 isoform 4
NM_001378158.1 NP_001365087.1 X-ray radiation resistance-associated protein 1 isoform 5
NM_001378159.1 NP_001365088.1 X-ray radiation resistance-associated protein 1 isoform 6
NM_001378160.1 NP_001365089.1 X-ray radiation resistance-associated protein 1 isoform 7
NM_001378161.1 NP_001365090.1 X-ray radiation resistance-associated protein 1 isoform 8
NM_001378162.1 NP_001365091.1 X-ray radiation resistance-associated protein 1 isoform 9
NM_001378163.1 NP_001365092.1 X-ray radiation resistance-associated protein 1 isoform 10
NM_001378164.1 NP_001365093.1 X-ray radiation resistance-associated protein 1 isoform 10
NM_001378165.1 NP_001365094.1 X-ray radiation resistance-associated protein 1 isoform 11
NM_001378166.1 NP_001365095.1 X-ray radiation resistance-associated protein 1 isoform 11
NM_001378167.1 NP_001365096.1 X-ray radiation resistance-associated protein 1 isoform 11
NM_001378168.1 NP_001365097.1 X-ray radiation resistance-associated protein 1 isoform 12
NM_001378169.1 NP_001365098.1 X-ray radiation resistance-associated protein 1 isoform 13
NM_001378170.1 NP_001365099.1 X-ray radiation resistance-associated protein 1 isoform 14
NM_001378171.1 NP_001365100.1 X-ray radiation resistance-associated protein 1 isoform 14
NM_001378172.1 NP_001365101.1 X-ray radiation resistance-associated protein 1 isoform 15
NM_001378173.1 NP_001365102.1 X-ray radiation resistance-associated protein 1 isoform 15
NM_001378174.1 NP_001365103.1 X-ray radiation resistance-associated protein 1 isoform 16
NM_001378175.1 NP_001365104.1 X-ray radiation resistance-associated protein 1 isoform 16
NM_001378176.1 NP_001365105.1 X-ray radiation resistance-associated protein 1 isoform 16
NM_182969.4 NP_892014.1 X-ray radiation resistance-associated protein 1 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in response to X-ray IDA
IDA: Inferred from direct assay
12908878 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12908878 GOA
located in nucleus IDA
IDA: Inferred from direct assay
12908878 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

XRRA1 Protein Structure

LRR_1

LRR_1: Leucine Rich Repeat (188 - 206)

  • 0
  • 200
  • 400
  • 600
  • 792 a.a.
Protein Preferred Names Protein Names

X-ray radiation resistance-associated protein 1

Related Diseases

Diseases Alias
Short-Rib Thoracic Dysplasia 8 With Or Without Polydactyly

  • SRTD8

  • Srps6

  • Short Rib-Polydactyly Syndrome Type Vi

  • Short Rib-Polydactyly Syndrome, Type Vi

  • Srps Type Vi
Brain Glioblastoma Multiforme

  • Brain Glioblastoma

  • Glioblastoma Multiforme Of Brain

  • Glioblastoma Nos
Retinitis Pigmentosa 10

  • RP10

  • Retinitis Pigmentosa-10

  • Retinitis Pigmentosa, Type 10
Familial Thyroid Dyshormonogenesis

  • Thyroid Dyshormonogenesis

  • Familial Dyshormonogenetic Goiter
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15904 XRRA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta XRRA1 VGNC VGNC:97846
Felis catus XRRA1 VGNC VGNC:67124
Mus musculus XRRA1 MGD MGI:2181647
Canis familiaris XRRA1 VGNC VGNC:48473
Bos taurus XRRA1 VGNC VGNC:37010
Rattus norvegicus XRRA1 RGD RGD:1305502
Others XRRA1 NCBI