GPAT2 - glycerol-3-phosphate acyltransferase 2, mitochondrial Gene

Also Known as CT123

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 150763

About GPAT2

Cytogenetic location: 2q11.2 Genomic coordinates (GRCh38): 2:96,021,946-96,036,265 (from NCBI)

This gene has 12 transcripts (splice variants), 191 orthologues and 2 paralogues. Broad expression in testis (RPKM 7.1), spleen (RPKM 3.6) and 22 other tissues.

Summary

Enables glycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in several processes, including glycerol-3-phosphate metabolic process; glycerolipid biosynthetic process; and piRNA biosynthetic process. Predicted to be located in mitochondrial outer membrane. Predicted to be active in mitochondrial membrane. [provided by Alliance of Genome Resources, Apr 2022]

GPAT2 Products (9)

mRNA Protein Name
NM_001321525.2 NP_001308454.1 glycerol-3-phosphate acyltransferase 2, mitochondrial isoform 2
NM_001321526.2 NP_001308455.1 glycerol-3-phosphate acyltransferase 2, mitochondrial isoform 2
NM_001321527.2 NP_001308456.1 glycerol-3-phosphate acyltransferase 2, mitochondrial isoform 2
NM_001321528.2 NP_001308457.1 glycerol-3-phosphate acyltransferase 2, mitochondrial isoform 3
NM_001321529.2 NP_001308458.1 glycerol-3-phosphate acyltransferase 2, mitochondrial isoform 4
NM_001321530.2 NP_001308459.1 glycerol-3-phosphate acyltransferase 2, mitochondrial isoform 5
NM_001321531.2 NP_001308460.1 glycerol-3-phosphate acyltransferase 2, mitochondrial isoform 6
NM_001389639.1 NP_001376568.1 glycerol-3-phosphate acyltransferase 2, mitochondrial isoform 9
NM_207328.4 NP_997211.2 glycerol-3-phosphate acyltransferase 2, mitochondrial isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables glycerol-3-phosphate O-acyltransferase activity EXP
EXP: Inferred from Experiment
18238778 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycerol-3-phosphate acyltransferase 2, mitochondrial

  • 1-acylglycerol-3-phosphate O-acyltransferase GPAT2

Related Diseases

Diseases Alias
Coenzyme Q10 Deficiency, Primary, 9

  • COQ10D9

  • Primary Coenzyme Q10 Deficiency 9
Fetal Akinesia Deformation Sequence 4

  • FADS4

  • Fetal Akinesia Deformation Sequence Syndrome 4

  • Akinesia, Fetal, Deformation Sequence, Type 4
Complete Generalized Lipodystrophy
Lipodystrophy, Congenital Generalized, Type 2

  • Congenital Generalized Lipodystrophy Type 2

  • CGL2

  • Berardinelli-Seip Congenital Lipodystrophy Type 2

  • Berardinelli-Seip Syndrome

  • Brunzell Syndrome Bscl2-Related

  • Total Lipodystrophy And Acromegaloid Gigantism

  • Berardinelli-Seip Congenital Lipodystrophy, Type 2

  • Seip Syndrome

  • Berardinelli Syndrome

  • Lipodystrophy, Total, And Acromegaloid Gigantism

  • Lipoatrophic Diabetes, Congenital

  • Lipodystrophy, Berardinelli-Seip Congenital, Type 2

  • Brunzell Syndrome, Bscl2-Related

  • Congenital Lipoatrophic Diabetes

  • Congenital Generalized Lipodystrophy 2

  • Lipoatrophic Diabetes

  • Lipodystrophy Berardinelli Type

  • Familial Generalized Lipodystrophy

  • Lipoatrophic Diabetes Mellitus

  • Familial Partial Lipodystrophy, Type 2
Congenital Generalized Lipodystrophy

  • Berardinelli-Seip Congenital Lipodystrophy

  • Berardinelli-Seip Syndrome

  • Brunzell Syndrome

  • Bscl

  • Generalized Lipodystrophy

  • Lipodystrophy, Congenital Generalized

  • Seip Syndrome

  • Total Lipodystrophy

  • Cgl

  • Lipoatrophic Diabetes

  • Lipodystrophy, Generalized, Congenital

  • Familial Generalized Lipodystrophy

  • Congenital Generalized Lipodystrophy Type 2

  • Lipoatrophic Diabetes Mellitus

  • Familial Partial Lipodystrophy, Type 2
Fetal Akinesia Deformation Sequence 1

  • Fetal Akinesia Deformation Sequence

  • Fads

  • Fetal Akinesia Sequence

  • FADS1

  • Arthrogryposis Multiplex Congenita With Pulmonary Hypoplasia

  • Pena-Shokeir Syndrome Type 1

  • Fetal Akinesia Deformation Sequence Syndrome

  • Arthrogryposis Multiplex Congenita-Pulmonary Hypoplasia Syndrome

  • Arthrogryposis Multiplex Congenita Pulmonary Hypoplasia

  • Pena-Shokeir Syndrome, Type I

  • Foetal Akinesia Deformation Sequence Syndrome

  • Foetal Akinesia Sequence

  • Fetal Akinesia Deformation Sequence Syndrome 1

  • Pena-Shokeir Syndrome, Type 1

  • Pena Shokeir Syndrome, Type 1

  • Akinesia, Fetal, Deformation Sequence

  • Akinesia, Fetal, Deformation Sequence, Type 1

  • Pena-Shokeir Syndrome Type I
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05616 GPAT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus GPAT2 VGNC VGNC:62653
Rattus norvegicus GPAT2 RGD RGD:1304904
Canis familiaris GPAT2 VGNC VGNC:41362
Bos taurus GPAT2 VGNC VGNC:29512
Mus musculus GPAT2 MGD MGI:2684962
Macaca mulatta GPAT2 VGNC VGNC:73018
Others GPAT2 NCBI