Ndst1 - N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 Gene

Enables deacetylase activity and sulfotransferase activity. Acts upstream of or within several processes, including animal organ development; positive regulation of signal transduction; and protein sulfation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including alimentary system; future brain; integumental system; nervous system; and respiratory system. Used to study DiGeorge syndrome; congenital diaphragmatic hernia; and newborn respiratory distress syndrome. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human NDST1 (N-deacetylase and N-sulfotransferase 1). [provided by Alliance of Genome Resources, Apr 2022]