USP51 - ubiquitin specific peptidase 51 Gene
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 158880
About USP51
This gene has 2 transcripts (splice variants), 46 orthologues and 71 paralogues. Broad expression in thyroid (RPKM 4.9), ovary (RPKM 3.8) and 23 other tissues.
Summary
Enables chromatin binding activity; histone binding activity; and thiol-dependent Deubiquitinase. Involved in histone deubiquitination; regulation of cell cycle process; and regulation of double-strand break repair. Predicted to be located in chromosome. [provided by Alliance of Genome Resources, Apr 2022]
USP51 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_201286.4 | NP_958443.1 | ubiquitin carboxyl-terminal hydrolase 51 |
USP51 Protein Structure
zf-UBP
zf-UBP: Zn-finger in ubiquitin-hydrolases and other protein (236 - 296)
UCH
UCH: Ubiquitin carboxyl-terminal hydrolase (363 - 703)
- 0
- 200
- 400
- 600
- 711 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
ubiquitin carboxyl-terminal hydrolase 51 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Non-Syndromic X-Linked Intellectual Disability 99 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(3)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS15563 | USP51 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS19752 | Usp51 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS26249 | Usp51 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | USP51 | MGD | MGI:3588217 |
| Rattus norvegicus | USP51 | RGD | RGD:1562211 |
| Others | USP51 | NCBI |
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