Hadhb - hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta Gene

Also Known as TP-beta

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171155

Summary

Enables acetyl-CoA C-acyltransferase activity. Involved in fatty acid beta-oxidation. Located in mitochondrion. Part of mitochondrial fatty acid beta-oxidation multienzyme complex. Human ortholog(s) of this gene implicated in Mitochondrial Metabolism disease and mitochondrial trifunctional protein deficiency. Orthologous to human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Hadhb Products (1)

mRNA Protein Name
NM_133618.3 NP_598302.1 trifunctional enzyme subunit beta, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables acetyl-CoA C-acyltransferase activity IDA
IDA: Inferred from direct assay
1730633 RGD
enables protein-containing complex binding IMP
IMP: Inferred from mutant phenotype
20132223 RGD
Biological Process GO Annotation Evidence References Source
involved in fatty acid beta-oxidation IDA
IDA: Inferred from direct assay
1730633 RGD
Cellular Component GO Annotation Evidence References Source
part of mitochondrial fatty acid beta-oxidation multienzyme complex IDA
IDA: Inferred from direct assay
1730633 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

trifunctional enzyme subunit beta, mitochondrial

  • hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit

  • hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit

  • mitochon

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05991 HADHB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18664 Hadhb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25150 Hadhb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hadhb NCBI NCBI:3032