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ZNF292 - zinc finger protein 292 Gene

Also Known as MRD63; MRD64; ZN-16; Zn-15; ZFP292; Nbla00365; bA393I2.3

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 23036

About ZNF292

Cytogenetic location: 6q14.3 Genomic coordinates (GRCh38): 6:87,155,565-87,265,943 (from NCBI)

This gene has 16 transcripts (splice variants), 292 orthologues, 2 paralogues and is associated with 2 phenotypes. Ubiquitous expression in bone marrow (RPKM 4.8), ovary (RPKM 3.8) and 25 other tissues.

Summary

This gene encodes a growth hormone-dependent, zinc finger transcription factor that functions as a tumor suppressor. Naturally occurring mutations in this gene are associated with gastric Cancer, colorectal Cancer, and chronic lymphocytic leukemia. [provided by RefSeq, May 2017]

ZNF292 Products (2)

mRNA	Protein	Name
NM_001351444.2	NP_001338373.1	zinc finger protein 292 isoform 2
NM_015021.3	NP_055836.1	zinc finger protein 292 isoform 1

ZNF292 Protein Structure

zf-C2H2_4

zf-C2H2

0
500
1000
1500
2000
2500
2723 a.a.

Protein Preferred Names	Protein Names
zinc finger protein 292	16 zinc-finger domain protein

Related Diseases

Diseases	Alias
Intellectual Developmental Disorder, Autosomal Dominant 64	MRD64 Mental Retardation, Autosomal Dominant 64
B-Lymphoblastic Leukemia/Lymphoma With Tcf3-Pbx1	B Acute Lymphoblastic Leukemia With T(1 19)(Q23 P13.3) E2a-Pbx1 (Tcf3-Pbx1) B-All With Tcf3-Pbx1 B-Lymphoblastic Leukemia/Lymphoma With T(1 19)(Q23 P13.3) Tcf3-Pbx1
Microcephaly	Microencephaly Microcephalus Microcephalic Nanocephaly Congenital Microcephaly Brain Hypoplasia Brain Nondevelopment Cephalic Hypoplasia Undeveloped Cerebrum Undeveloped Brain Micrencephalon Micrencephaly
Autism Spectrum Disorder	Asd Autism Spectrum Disorders Autistic Continuum Pervasive Developmental Disorder Pervasive Development Disorder Autistic Behavior Autistic Disorder Autistic Autistic Disorder Of Childhood Onset Infantile Autism Childhood Autism Kanner Syndrome Pervasive Developmental Delay Nos Pervasive Developmental Disorder, Not Otherwise Specified
Autism	Autistic Disorder Autism Susceptibility 1 Childhood Autism Autistic Disorder Of Childhood Onset Infantile Autism Kanner'S Syndrome Autistic
Attention Deficit-Hyperactivity Disorder	Attention Deficit Hyperactivity Disorder ADHD Attention Deficit Disorder Attention Deficit-Hyperactivity Disorder, Susceptibility To Attention Deficit Disorder With Hyperactivity Hyperkinetic Disorder Hyperactivity Of Childhood Attention-Deficit/Hyperactivity Disorder Add Addh Attention Deficit Attention Deficit Disorder Of Childhood With Hyperactivity Attention Deficit Disorder With Hyperactivity Syndrome Hyperkinetic Syndrome Attention-Deficit Hyperactivity Disorder Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type Disturbance Of Activity And Attention Disorder Of Activity And Attention Adhd - [Attention Deficit Hyperactivity Disorder] Hyperkinetic Disorders Disorder Of Activity And Attention With Hyperkinesia Attention Deficit Syndrome With Hyperactivity
Noonan Syndrome 1	Noonan Syndrome NS1 Male Turner Syndrome Female Pseudo-Turner Syndrome Turner Phenotype With Normal Karyotype Noonan Syndrome With Pigmented Villonodular Synovitis Turner'S Phenotype, Karyotype Normal Familial Turner Syndrome Noonan'S Syndrome Noonan-Ehmke Syndrome Ns Pseudo-Ullrich-Turner Syndrome Turner Syndrome In Female With X Chromosome Turner-Like Syndrome Ullrich-Noonan Syndrome Noonan-Like/Multiple Giant Cell Lesion Syndrome Noonan Syndrome-Like Disorder With Multiple Giant Cell Lesions Pterygium Colli Syndrome Noonan Syndrome, Type 1 Turner Syndrome, Male

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16122	ZNF292 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	ZNF292	VGNC	VGNC:67286
Bos taurus	ZNF292	VGNC	VGNC:37239
Rattus norvegicus	ZNF292	RGD	RGD:61931
Macaca mulatta	ZNF292	VGNC	VGNC:79136
Mus musculus	ZNF292	MGD	MGI:1353423
Canis familiaris	ZNF292	VGNC	VGNC:48691
Others	ZNF292	NCBI