Rgs7 - regulator of G protein signaling 7 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 24012

Summary

Predicted to enable G-protein alpha-subunit binding activity; G-protein beta-subunit binding activity; and GTPase activator activity. Involved in regulation of postsynaptic membrane potential. Acts upstream of or within G protein-coupled receptor signaling pathway and regulation of G protein-coupled receptor signaling pathway. Located in several cellular components, including dendrite terminus; glutamatergic synapse; and nucleus. Is active in postsynaptic membrane and presynapse. Is expressed in bone; foot mesenchyme; nervous system; pelvic girdle skeleton; and sensory organ. Orthologous to human RGS7 (regulator of G protein signaling 7). [provided by Alliance of Genome Resources, Apr 2022]

Rgs7 Products (4)

mRNA Protein Name
NM_001199003.1 NP_001185932.1 regulator of G-protein signaling 7 isoform 2
NM_001347195.1 NP_001334124.1 regulator of G-protein signaling 7 isoform 3
NM_001357129.1 NP_001344058.1 regulator of G-protein signaling 7 isoform 4
NM_011880.3 NP_036010.2 regulator of G-protein signaling 7 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
25792749 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15897264 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
15897264 MGI
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
25792749 MGI
acts upstream of or within regulation of G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
22689652 MGI
acts upstream of or within regulation of G protein-coupled receptor signaling pathway IGI
IGI: Inferred from genetic interaction
22689652 MGI
involved in regulation of postsynaptic membrane potential IDA
IDA: Inferred from direct assay
24755289 MGI
involved in regulation of postsynaptic membrane potential IMP
IMP: Inferred from mutant phenotype
24755289 MGI
Cellular Component GO Annotation Evidence References Source
is active in cell tip IDA
IDA: Inferred from direct assay
25997951 MGI
is active in dendrite IDA
IDA: Inferred from direct assay
25997951 MGI
located in dendrite terminus IDA
IDA: Inferred from direct assay
22689652 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
24755289 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
24755289 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15897264 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
15897264 MGI
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
23804514 MGI
is active in presynapse IDA
IDA: Inferred from direct assay
27965545 MGI
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
23804514 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

regulator of G-protein signaling 7

  • Regulator of G-protein signaling 7 (RGS7)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-70075 CCG-63808 Inhibitor 98.0% Unkown
HY-RS11925 RGS7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rgs7 NCBI NCBI:6000