Sgcd - sarcoglycan, delta (dystrophin-associated glycoprotein) Gene

Also Known as 35DAG; SG-delta; delta-SG; A530047J11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 24052

Summary

Acts upstream of or within several processes, including calcium-mediated signaling; cardiac muscle cell contraction; and heart development. Located in sarcolemma and sarcoplasmic reticulum. Part of sarcoglycan complex. Is expressed in brain; mandible; and maxilla. Used to study autosomal recessive limb-girdle muscular dystrophy type 2F and dilated cardiomyopathy 1L. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2F; dilated cardiomyopathy 1L; and muscular dystrophy. Orthologous to human SGCD (sarcoglycan delta). [provided by Alliance of Genome Resources, Apr 2022]

Sgcd Products (1)

mRNA Protein Name
NM_011891.5 NP_036021.1 delta-sarcoglycan

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12189167 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within calcium ion homeostasis IMP
IMP: Inferred from mutant phenotype
19931597 MGI
acts upstream of or within calcium-mediated signaling IMP
IMP: Inferred from mutant phenotype
19931597 MGI
acts upstream of or within cardiac muscle cell contraction IMP
IMP: Inferred from mutant phenotype
10481911 MGI
acts upstream of or within cardiac muscle cell development IMP
IMP: Inferred from mutant phenotype
23695275 MGI
acts upstream of or within cardiac muscle contraction IMP
IMP: Inferred from mutant phenotype
23695275 MGI
acts upstream of or within coronary vasculature morphogenesis IMP
IMP: Inferred from mutant phenotype
10481911 MGI
acts upstream of or within heart process IMP
IMP: Inferred from mutant phenotype
23695275 MGI
acts upstream of or within protein-containing complex localization IMP
IMP: Inferred from mutant phenotype
10481911 MGI
Cellular Component GO Annotation Evidence References Source
part of dystroglycan complex IDA
IDA: Inferred from direct assay
10678176 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
10481911 MGI
part of sarcoglycan complex IDA
IDA: Inferred from direct assay
12189167 MGI
located in sarcolemma IDA
IDA: Inferred from direct assay
10481911 MGI
located in sarcoplasmic reticulum IDA
IDA: Inferred from direct assay
16403451 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

delta-sarcoglycan

  • 35 kDa dystrophin-associated glycoprotein

  • sarcoglycan, delta (35kD dystrophin-associated glycoprotein)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12792 SGCD Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sgcd NCBI NCBI:6444