Xirp2 - xin actin-binding repeat containing 2 Gene

Also Known as Xin2; Cmya3; Gm352; 2310003D02Rik; 2310008C07Rik; A530024P18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 241431

Summary

Enables alpha-actinin binding activity. Acts upstream of or within cardiac muscle tissue morphogenesis; cell-cell junction organization; and ventricular septum development. Located in Z disc. Is expressed in heart; lung; and skeletal muscle. Orthologous to human XIRP2 (xin actin binding repeat containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Xirp2 Products (2)

mRNA Protein Name
NM_001024618.2 NP_001019789.1 xin actin-binding repeat-containing protein 2 isoform 1
NM_001083919.1 NP_001077388.1 xin actin-binding repeat-containing protein 2 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables alpha-actinin binding IDA
IDA: Inferred from direct assay
17046827 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21689717 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cardiac muscle tissue morphogenesis IMP
IMP: Inferred from mutant phenotype
20360251 MGI
acts upstream of or within cell-cell junction organization IMP
IMP: Inferred from mutant phenotype
20360251 MGI
involved in positive regulation of protein localization IMP
IMP: Inferred from mutant phenotype
37294664 MGI
involved in regulation of actin filament organization IMP
IMP: Inferred from mutant phenotype
25772365 MGI
acts upstream of or within ventricular septum development IMP
IMP: Inferred from mutant phenotype
20360251 MGI
Cellular Component GO Annotation Evidence References Source
located in Z disc IDA
IDA: Inferred from direct assay
17046827 MGI
located in cell-cell junction IDA
IDA: Inferred from direct assay
37294664 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

xin actin-binding repeat-containing protein 2

  • Xin actin-binding repeat containing 2 short splice form

  • beta-xin

  • cardiomyopathy associated 3

  • cardiomyopathy-associated protein 3

  • mXinbeta

  • myogenic MEF2-activated Xin-related protein

  • myomaxin

  • xeplin

  • xin-beta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15877 XIRP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Xirp2 NCBI NCBI:129446