Acaa1a - acetyl-CoA acyltransferase 1A Gene

Rattus norvegicus

Also known as Acaa; Acaa1; Pktaa

Gene ID: 24157 | Gene type: protein coding

About Acaa1a

Summary

Enables acetyl-CoA C-acyltransferase activity; acetyl-CoA C-myristoyltransferase activity; and palmitoyl-CoA oxidase activity. Involved in several processes, including monocarboxylic acid metabolic process; response to nutrient; and response to steroid hormone. Located in peroxisome. Orthologous to human ACAA1 (acetyl-CoA Acyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Acaa1a Products(2)

mRNA	Protein	Name
NM_001395662.1	NP_001382591.1	3-ketoacyl-CoA thiolase A, peroxisomal isoform 2
NM_012489.3	NP_036621.2	3-ketoacyl-CoA thiolase A, peroxisomal isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables acetyl-CoA C-acyltransferase activity	IDA IDA: Inferred from direct assay	9325339	RGD
enables acetyl-CoA C-myristoyltransferase activity	IDA IDA: Inferred from direct assay	9325339	RGD
enables palmitoyl-CoA oxidase activity	IGI IGI: Inferred from genetic interaction	2882519	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in bile acid metabolic process	IDA IDA: Inferred from direct assay	9325339	RGD
involved in fatty acid beta-oxidation	IDA IDA: Inferred from direct assay	9325339	RGD
involved in fatty acid beta-oxidation	IGI IGI: Inferred from genetic interaction	2882519	RGD
involved in response to nutrient	IDA IDA: Inferred from direct assay	8954134	RGD
involved in response to steroid hormone	IDA IDA: Inferred from direct assay	9101583	RGD
involved in response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	2307679	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in peroxisome	IDA IDA: Inferred from direct assay	9325339	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

3-ketoacyl-CoA thiolase A, peroxisomal

Acetyl-CoA acyltransferase 3-oxo acyl-CoA thiolase A peroxisomal	acetyl-CoA C-myristoyltransferase
acetyl-CoA acyltransferase 1	acetyl-CoA acyltransferase 3-oxo acyl-CoA thiolase A 1 peroxisomal
acetyl-CoA acyltransferase A	acetyl-CoA acyltransferase

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00117	ACAA1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

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