2. Gene
  3. Cyp2r1 - cytochrome P450, family 2, subfamily r, polypeptide 1 Gene

Cyp2r1 - cytochrome P450, family 2, subfamily r, polypeptide 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 244209 | Gene type: protein coding

About Cyp2r1

Summary

Enables vitamin D3 25-hydroxylase activity. Acts upstream of or within vitamin D metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in embryo; liver; and testis. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus and vitamin D-dependent rickets type 1B. Orthologous to human CYP2R1 (Cytochrome P450 family 2 subfamily R member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp2r1 Products(1)

mRNA Protein Name
NM_177382.4 NP_796356.2 vitamin D 25-hydroxylase
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables vitamin D3 25-hydroxylase activity IDA
IDA: Inferred from direct assay
12867411 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within vitamin D metabolic process IDA
IDA: Inferred from direct assay
12867411 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vitamin D 25-hydroxylase

cytochrome P450, 2r1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03466 CYP2R1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cyp2r1 NCBI NCBI:120227