Mtss2 - MTSS I-BAR domain containing 2 Gene

Also Known as ABBA; Mtss1l

Species: Mus musculus

Gene Type: protein coding
Gene ID: 244654

Summary

Enables actin monomer binding activity; phosphatidylinositol-4,5-bisphosphate binding activity; and small GTPase binding activity. Acts upstream of or within lamellipodium organization and membrane organization. Located in several cellular components, including cortical actin cytoskeleton; lamellipodium; and ruffle. Is expressed in several structures, including central nervous system; gut; musculoskeletal system; otic capsule; and vibrissa. Orthologous to human MTSS2 (MTSS I-BAR domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Mtss2 Products (4)

mRNA Protein Name
NM_001310591.1 NP_001297520.1 protein MTSS 2 isoform 2
NM_198625.2 NP_941027.1 protein MTSS 2 isoform 1
NM_001310591.1 NP_001297520.1 protein MTSS 2 isoform 2
NM_198625.2 NP_941027.1 protein MTSS 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin monomer binding IDA
IDA: Inferred from direct assay
18413296 MGI
enables phosphatidylinositol-4,5-bisphosphate binding IDA
IDA: Inferred from direct assay
18413296 MGI
enables small GTPase binding IDA
IDA: Inferred from direct assay
18413296 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within lamellipodium organization IMP
IMP: Inferred from mutant phenotype
18413296 MGI
acts upstream of or within membrane organization IDA
IDA: Inferred from direct assay
18413296 MGI
Cellular Component GO Annotation Evidence References Source
located in cortical actin cytoskeleton IDA
IDA: Inferred from direct assay
18413296 MGI
located in lamellipodium IDA
IDA: Inferred from direct assay
18413296 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
18413296 MGI
located in ruffle IDA
IDA: Inferred from direct assay
18413296 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein MTSS 2

  • MTSS1-like protein

  • metastasis suppressor 1-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08821 MTSS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mtss2 NCBI NCBI:92154