2. Gene
  3. Mtss2 - MTSS I-BAR domain containing 2 Gene

Mtss2 - MTSS I-BAR domain containing 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ABBA; Mtss1l

Gene ID: 244654 | Gene type: protein coding

About Mtss2

Summary

Enables actin monomer binding activity; phosphatidylinositol-4,5-bisphosphate binding activity; and small GTPase binding activity. Acts upstream of or within lamellipodium organization and membrane organization. Located in several cellular components, including cortical actin cytoskeleton; lamellipodium; and ruffle. Is expressed in several structures, including central nervous system; gut; musculoskeletal system; otic capsule; and vibrissa. Orthologous to human MTSS2 (MTSS I-BAR domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Mtss2 Products(4)

mRNA Protein Name
NM_001310591.1 NP_001297520.1 protein MTSS 2 isoform 2
NM_198625.2 NP_941027.1 protein MTSS 2 isoform 1
NM_001310591.1 NP_001297520.1 protein MTSS 2 isoform 2
NM_198625.2 NP_941027.1 protein MTSS 2 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables actin monomer binding IDA
IDA: Inferred from direct assay
18413296 MGI
enables phosphatidylinositol-4,5-bisphosphate binding IDA
IDA: Inferred from direct assay
18413296 MGI
enables small GTPase binding IDA
IDA: Inferred from direct assay
18413296 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within lamellipodium organization IMP
IMP: Inferred from mutant phenotype
18413296 MGI
acts upstream of or within membrane organization IDA
IDA: Inferred from direct assay
18413296 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cortical actin cytoskeleton IDA
IDA: Inferred from direct assay
18413296 MGI
located in lamellipodium IDA
IDA: Inferred from direct assay
18413296 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
18413296 MGI
located in ruffle IDA
IDA: Inferred from direct assay
18413296 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein MTSS 2

MTSS1-like protein

metastasis suppressor 1-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08821 MTSS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mtss2 NCBI NCBI:92154