Bsx - brain specific homeobox Gene

Mus musculus

Also known as Bsx1a; Bsx1b

Gene ID: 244813 | Gene type: protein coding

About Bsx

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including eating behavior; mammary gland involution; and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in brain; metanephros; and renal vasculature. Orthologous to human BSX (brain specific homeobox). [provided by Alliance of Genome Resources, Apr 2022]

Bsx Products(1)

mRNA	Protein	Name
NM_178245.3	NP_839976.1	brain-specific homeobox protein homolog

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	17353277	MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	17353277	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	17550780	MGI
enables sequence-specific DNA binding	IDA IDA: Inferred from direct assay	17550780	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within eating behavior	IMP IMP: Inferred from mutant phenotype	17550780	MGI
acts upstream of or within locomotory behavior	IMP IMP: Inferred from mutant phenotype	17550780	MGI
acts upstream of or within mammary gland involution	IMP IMP: Inferred from mutant phenotype	17485440	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	17550780	MGI
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	17353277	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IGI IGI: Inferred from genetic interaction	17550780	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	17550780	MGI
part of transcription regulator complex	IDA IDA: Inferred from direct assay	17550780	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

brain-specific homeobox protein homolog

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01650	BSX Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Bsx	NCBI	NCBI:390259

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