Akap9 - A-kinase anchoring protein 9 Gene

Also Known as Gisp; CG-NAP; Yotiao

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 246150

Summary

Enables protein kinase A regulatory subunit binding activity. Involved in negative regulation of Adenylate Cyclase activity and response to electrical stimulus. Located in dendritic branch; neuronal cell body; and synaptic membrane. Is extrinsic component of postsynaptic density membrane. Human ortholog(s) of this gene implicated in long QT syndrome 11. Orthologous to human AKAP9 (A-kinase anchoring protein 9). [provided by Alliance of Genome Resources, Apr 2022]

Akap9 Products (1)

mRNA Protein Name
NM_001037093.2 NP_001032170.2 A-kinase anchor protein 9

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10618500 RGD
enables protein kinase A regulatory subunit binding IPI
IPI: Inferred from physical interaction
10618500 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of adenylate cyclase activity IMP
IMP: Inferred from mutant phenotype
18772391 RGD
involved in response to electrical stimulus IEP
IEP: Inferred from expression pattern
14732469 RGD
Cellular Component GO Annotation Evidence References Source
located in dendritic branch IDA
IDA: Inferred from direct assay
10618500 RGD
is active in extrinsic component of postsynaptic density membrane IDA
IDA: Inferred from direct assay
9482789 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
10618500 RGD
located in synaptic membrane IDA
IDA: Inferred from direct assay
10618500 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

A-kinase anchor protein 9

  • A kinase (PRKA) anchor protein (yotiao) 9

  • A kinase (PRKA) anchor protein 9

  • GABA-B receptor-interacting scaffolding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00525 AKAP9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Akap9 NCBI NCBI:10142