Slc36a2 - solute carrier family 36 member 2 Gene

Rattus norvegicus

Also known as Pat2; Tramd1

Gene ID: 246235 | Gene type: protein coding

About Slc36a2

Summary

Enables glycine transmembrane transporter activity. Involved in amino acid transmembrane transport and regulation of ion transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in iminoglycinuria. Orthologous to human SLC36A2 (solute carrier family 36 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc36a2 Products(1)

mRNA	Protein	Name
NM_139339.2	NP_647555.2	proton-coupled amino acid transporter 2

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables amino acid:proton symporter activity	IDA IDA: Inferred from direct assay	12727219	RGD
enables glycine transmembrane transporter activity	IDA IDA: Inferred from direct assay	12727219	RGD
enables proline:proton symporter activity	IDA IDA: Inferred from direct assay	12727219	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in amino acid export across plasma membrane	IDA IDA: Inferred from direct assay	20691150	RGD
involved in positive regulation of glycine import across plasma membrane	IDA IDA: Inferred from direct assay	20691150	RGD
involved in proline transmembrane transport	IDA IDA: Inferred from direct assay	20691150	RGD
involved in regulation of proline transport	IDA IDA: Inferred from direct assay	20691150	RGD
involved in regulation of proton transport	IDA IDA: Inferred from direct assay	20691150	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

proton-coupled amino acid transporter 2

proton/amino acid transporter 2	rPAT2
solute carrier family 36 (proton/amino acid symporter), member 2	tramdorin-1
transmembrane domain rich protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13211	SLC36A2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc36a2	NCBI	NCBI:153201

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